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Lactose intolerance is the ancestral state of all humans before the recent evolution of lactase persistence in some cultures, which extends lactose tolerance into adulthood. [9] Lactase persistence evolved in several populations independently, probably as an adaptation to the domestication of dairy animals around 10,000 years ago.
Added Portugal and Spain to the 60-70% range that the sources claim. There are other inaccuracies in the map. 08:54, 12 July 2017: 512 × 402 (124 KB) Joe Roe: Recoloured sample locations based on the actual value at that location. 21:13, 3 July 2017: 512 × 402 (94 KB) Joe Roe: User created page with UploadWizard
Lactase persistence or lactose tolerance is the continued activity of the lactase enzyme in adulthood, allowing the digestion of lactose in milk. In most mammals , the activity of the enzyme is dramatically reduced after weaning . [ 1 ]
[h] People of the Nordic Bronze Age and Corded Ware show the highest lactose tolerance among Bronze Age Europeans. [i] The study also found a close genetic relationship between the Corded Ware culture and the Sintashta culture, suggesting that the Sintashta culture emerged as a result of an eastward expansion of Corded Ware peoples.
Lactase (EC 3.2.1.108) is an enzyme produced by many organisms and is essential to the complete digestion of whole milk.It breaks down the sugar lactose into its component parts, galactose and glucose.
This is an autosomal recessive disorder and infants that can’t break down lactose have trouble with breastmilk, and develop diarrhea starting from birth. Sometimes, even those with lactase-persistence can develop temporary lactose intolerance as a result of infection or inflammation in the small intestine.
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In one study, five ancient DNA samples from Yamnaya sites had a frequency of over 25% of an allele that is associated with lactase persistence, conferring lactose tolerance into adulthood. [45]