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Biguanide (/ b aɪ ˈ ɡ w ɒ n aɪ d /) is the organic compound with the formula HN(C(NH)NH 2) 2. It is a colorless solid that dissolves in water to give a highly basic solution. It is a colorless solid that dissolves in water to give a highly basic solution.
Taking proguanil with food may lessen these side effects. [11] Proguanil should not be taken by people with severe renal impairment, pregnant women, or women who are breastfeeding children less than 5 kg. [12] There have also been reports of increased levels of liver enzymes, which may remain high for up to 4 weeks after completion of treatment ...
Opioid use during pregnancy may cause adverse outcomes for the women and unborn child. [11] Women who use opioids during pregnancy in a non-medical fashion are at a higher risk for premature birth, lower birth weight, still birth, specific birth defects, and withdrawal (neonatal abstinence syndrome). [11]
Drugs with shorter half-life's require more frequent administration to maintain the correct plasma concentrations, therefore potentially presenting more problems if levels of adherence and compliance are unreliable, but longer-lasting drugs can increase the development of resistance due to prolonged periods of low drug concentration.
[10] [11] However, many substances which are toxic for reproduction do not fall into any of these groups: lead compounds, for example, are considered to be toxic for reproduction [10] [11] given their adverse effects on the normal intellectual and psychomotor development of human babies and children.
Luigi Mangione, the man accused of gunning down UnitedHealthcare CEO Brian Thompson, will waive extradition to New York when he appears in court in Pennsylvania on Thursday, his attorney said ...
Phenformin is an antidiabetic drug from the biguanide class. It was marketed as DBI by Ciba-Geigy, but was withdrawn from most markets in the late 1970s due to a high risk of lactic acidosis, which was fatal in 50% of cases. Phenformin was developed in 1957 by Ungar, Freedman and Seymour Shapiro, working for the U.S. Vitamin Corporation ...
On Dec. 13, 2024, a coroner’s report concluded that “basic failures” to escalate her concerns led to her death from a “massive peritoneal hemorrhage” - just two days after giving birth ...