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Papanicolaou stain (also Papanicolaou's stain and Pap stain) is a multichromatic (multicolored) cytological staining technique developed by George Papanicolaou in 1942. [ 1 ] [ 2 ] [ 3 ] The Papanicolaou stain is one of the most widely used stains in cytology , [ 1 ] where it is used to aid pathologists in making a diagnosis.
Cytolysis would result in the image on the far right. Micrographs of osmotic pressure on red blood cells A human white blood cell (upper right) in water swells until it bursts (at ~14 seconds) Cytolysis , or osmotic lysis , occurs when a cell bursts due to an osmotic imbalance that has caused excess water to diffuse into the cell.
The Papanicolaou test (abbreviated as Pap test, also known as Pap smear (AE), [1] cervical smear (BE), cervical screening (BE), [2] or smear test (BE)) is a method of cervical screening used to detect potentially precancerous and cancerous processes in the cervix (opening of the uterus or womb) or, more rarely, anus (in both men and women). [3]
Pap smears are screening tools to detect any abnormal changes in cervical cells which may indicate cancer or HPV. How frequently you should get a Pap smear or HPV test - and what to expect during ...
[33] [28] The cells progress through the cell cycle and then decompose (cytolysis) within a week's time. Cytolysis occurs only in the presence of glycogen-containing cells, that is, when the epithelium is degraded to the upper intermediate cells and superficial cells. In this way, the cytoplasm is dissolved, while the cell nuclei remain. [33]
What to do if you get an abnormal pap smear result. If you get an abnormal result from your pap test, don’t panic: “Many women have abnormal cervical cancer screening results and an abnormal ...
Currently, the pap smear — in which cells taken from the cervix are examined by a doctor “for cervical cancer or cell changes,” per the National Cancer Institute — is the recommended ...
The most common investigation in this field is the Pap test, which is used to screen for potentially precancerous lesions of the cervix. Cytology can also be used to investigate disorders of the ovaries, uterus, vagina and vulva. Gynaecologic cytology makes frequent use of the Bethesda system in order to grade the results of HPV testing. [2]