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Lomustine (INN; abbreviated as CCNU; original brand name CeeNU, now marketed as Gleostine) is an alkylating nitrosourea compound used in chemotherapy. It is closely related to semustine and is in the same family as streptozotocin. It is a highly lipid-soluble drug, [3] thus it crosses the blood–brain barrier.
The chemotherapy drug gets absorbed by the cancer. By using the very same mechanisms that cancer cells use to grow and kill people, proponents believe IPT channels the chemotherapy drug directly inside the cancer cells leaving normal cells alone. [4] [5] Insulin therapy is not the same as IPT low-dose chemotherapy. Insulin on its own modulates ...
It is commonly given in oral form, which is more convenient for patients and has a lower cost compared with intravenous form used in conventional chemotherapy. [5] At a low concentration, the drugs primarily act on the tumor microenvironment including the tumor endothelial cells and immune cells.
An oral pill in clinical trials shows promising results in lung cancer patients with advanced disease. Lung cancer is the third most common cancer… Lung cancer pill outperforms chemotherapy in ...
Many biologics, such as chemotherapy drugs, are administered in a doctor's office and require extensive monitoring, further driving up costs." [6] Chemotherapy is usually delivered intravenously, although a number of agents can be administered orally (e.g. specialty drugs, melphalan (trade name Alkeran), busulfan, capecitabine).
Intensification chemotherapy is identical to consolidation chemotherapy but a different drug than the induction chemotherapy is used. [6]: 55–59 Combination chemotherapy involves treating a person with a number of different drugs simultaneously. The drugs differ in their mechanism and side-effects.
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Each drug is listed once (at present), though it might fall in more than one subsection. A full alphabetical listing is included after the categorical listing. The agents in this list are often combined into chemotherapy agent for polychemotherapy (combination chemotherapy).
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