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Leydig cells release a class of hormones called androgens (19-carbon steroids). [8] They secrete testosterone, androstenedione and dehydroepiandrosterone (DHEA), when stimulated by the luteinizing hormone (LH), which is released from the anterior pituitary in response to gonadotropin releasing hormone which in turn is released by the hypothalamus.
Sertoli cells function to nourish the developing sperm cells. They secrete androgen-binding protein, a binding protein which increases the concentration of testosterone. There are two types: convoluted and straight, convoluted toward the lateral side, and straight as the tubule comes medially to form ducts that will exit the testis.
The main male sex organs are the penis and the scrotum, which contains the testicles that produce semen and sperm, which, as part of sexual intercourse, fertilize an ovum in the female's body; the fertilized ovum develops into a fetus, which is later born as an infant. The corresponding system in females is the female reproductive system.
A low testosterone level (hypogonadism) in men may be treated with testosterone administration. Prostate cancer may be treated by removing the major source of testosterone: testicle removal (orchiectomy); or agents which block androgens from accessing their receptor: antiandrogens.
The Leydig cells are also capable of producing estradiol in addition to their main product testosterone. Estrogen has been found to be essential for spermatogenesis in animals. [ 32 ] [ 33 ] However, a man with estrogen insensitivity syndrome (a defective ERα ) was found produce sperm with a normal sperm count , albeit abnormally low sperm ...
Testosterone, which is produced by your testicles, “plays a key role in the development of characteristics like libido, and growth of the penis and testicles,” says Jamin Brahmbhatt, MD, a ...
s. Scrotum. sp. Corpus cavernosum urethrae. t. Testis in the place of its original formation. t’, together with the dotted lines above, indicates the direction in which the testis and epididymis descend from the abdomen into the scrotum. vd. Ductus deferens. vh. Ductus aberrans. vs. The vesicula seminalis.
Since the testicles are the main producers of testosterone, any damage or condition affecting the organs can affect testosterone. ... which are parts of the brain that tell the testicles to ...