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Heart failure with preserved ejection fraction (HFpEF) is a form of heart failure in which the ejection fraction – the percentage of the volume of blood ejected from the left ventricle with each heartbeat divided by the volume of blood when the left ventricle is maximally filled – is normal, defined as greater than 50%; [1] this may be measured by echocardiography or cardiac catheterization.
Dapagliflozin is an example of an SGLT-2 inhibitor, it is a competitive, highly selective inhibitor of SGLT. It acts via selective and potent inhibition of SGLT-2, and its activity is based on each patient's underlying blood sugar control and kidney function. The results are decreased kidney reabsorption of glucose, glucosuria effect increases ...
GIN has an International Guideline Library and registry, [7] one of the world's largest guideline libraries, [citation needed] containing regularly updated guidelines and publications of the GIN membership, as well as other guideline developers. The registry is open for all guideline developers to register their guidelines.
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[1] [2] Both SGLT1 and SGLT2 function as symporters, utilizing the energy from the sodium gradient created by the Na+/K+ ATPase to transport glucose against its concentration gradient. [ 2 ] [ 3 ] SGLT2, encoded by the SLC5A2 gene, is predominantly expressed in the S1 and S2 segments of the proximal renal tubule and is responsible for ...
Hyundai is recalling the 2022-2024 IONIQ 5 for a loss of drive power. Recalled Hyundai vehicles (145,235) 2022-2024 Hyundai IONIQ 5. 2023-2025 Hyundai IONIQ 6. 2023-2025 Genesis GV60.
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Sen. Mike Lee, R-Utah. Lee, who has served 14 years in the Senate and sits on the Judiciary Committee, was considered a top candidate for attorney general before Gaetz was chosen and could ...