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Zoledronic acid, also known as zoledronate and sold under the brand name Zometa among others, [7] by Novartis among others, is a medication used to treat a number of bone diseases. [3] These include osteoporosis , high blood calcium due to cancer , bone breakdown due to cancer, Paget's disease of bone [ 3 ] and Duchenne muscular dystrophy (DMD).
It concerns both human and animal vaccines. Although the emergence of a number of vaccine resistant pathogens has been well documented, this phenomenon is nevertheless much more rare and less of a concern than antimicrobial resistance. Vaccine resistance may be considered a special case of immune evasion, from the immunity conferred by the vaccine.
Both Pfizer and Moderna’s Omicron boosters are "bivalent" vaccines, meaning they protect against Omicron BA.5 and BA.4 subvariants and the original SARS-CoV-2 virus. "The goal of a COVID vaccine ...
BA.5, a new Omicron subvariant of the coronavirus, has become dominant, accounting for 65% of infections nationwide, according to the Centers for Disease Control and Prevention. Some experts have ...
In June 2022, Pfizer and Moderna developed bivalent vaccines to protect against the SARS-CoV-2 wild-type and the Omicron variant. The bivalent vaccines are well-tolerated and offer immunity to Omicron superior to previous mRNA vaccines. [268] In September 2022, the United States Food and Drug Administration (FDA) authorized the bivalent vaccines.
Though COVID-19 vaccines and boosters provide strong protection against severe disease, hospitalizations, and deaths, the quickly-spreading Omicron variant remains a significant challenge.
There are no human data yet on the new Omicron booster, but past research hints at an answer.
A light curve for Omicron 1 Canis Majoris, plotted from Hipparcos data [20]. The star itself is an orange K-type supergiant of spectral type K2.5 Iab and is an irregular variable star, varying between apparent magnitudes 3.78 and 3.99.