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  2. IFNW1 - Wikipedia

    en.wikipedia.org/wiki/IFNW1

    3467 n/a Ensembl ENSG00000177047 n/a UniProt P05000 n/a RefSeq (mRNA) NM_002177 n/a RefSeq (protein) NP_002168 n/a Location (UCSC) Chr 9: 21.14 – 21.14 Mb n/a PubMed search n/a Wikidata View/Edit Human Interferon omega-1 is a protein that is encoded by the IFNW1 gene. Introduction Interferon omega-1 (IFN-ω) is a subtype of the Interferon type I family. The Interferon Type 1 family is made ...

  3. Interferon - Wikipedia

    en.wikipedia.org/wiki/Interferon

    For example, in January 2001, the Food and Drug Administration (FDA) approved the use of PEGylated interferon-alpha in the USA; in this formulation, PEGylated interferon-alpha-2b (Pegintron), polyethylene glycol is linked to the interferon molecule to make the interferon last longer in the body. Approval for PEGylated interferon-alpha-2a ...

  4. Interferon type I - Wikipedia

    en.wikipedia.org/wiki/Interferon_type_I

    The type-I interferons (IFN) are cytokines which play essential roles in inflammation, immunoregulation, tumor cells recognition, and T-cell responses. In the human genome, a cluster of thirteen functional IFN genes is located at the 9p21.3 cytoband over approximately 400 kb including coding genes for IFNα (IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16 ...

  5. IFIT proteins - Wikipedia

    en.wikipedia.org/wiki/IFIT_proteins

    IFIT proteins (Interferon Induced proteins with tetratricopeptide repeats) are produced in the human body and are supposed to confer immunity against viral infections.These proteins are generally produced during viral infection by interferon treatment as well as during pathogen recognition (Pathogen associated molecular pattern recognition) by the immune system during infections.

  6. Interferon-stimulated gene - Wikipedia

    en.wikipedia.org/wiki/Interferon-stimulated_gene

    An interferon-stimulated gene (ISG) is a gene that can be expressed in response to stimulation by interferon. [ 1 ] [ 2 ] Interferons bind to receptors on the surface of a cell, initiating protein signaling pathways within the cell.

  7. Viral strategies for immune response evasion - Wikipedia

    en.wikipedia.org/wiki/Viral_strategies_for...

    The precise role of double-stranded (ds)RNA is still widely investigated as a central player in the Interferon System. Groups have found that positive-strand RNA viruses and dsRNA viruses produced significant amounts of dsRNA, but the precise methods mammalian cells leverage to distinguish between self vs. non-self dsRNA have yet to be uncovered.

  8. IFNA4 - Wikipedia

    en.wikipedia.org/wiki/IFNA4

    230398 Ensembl ENSG00000236637 ENSMUSG00000078355 UniProt P05014 Q810G1 RefSeq (mRNA) NM_021068 NM_206867 RefSeq (protein) NP_066546 NP_996750 Location (UCSC) Chr 9: 21.19 – 21.19 Mb Chr 4: 88.59 – 88.6 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Interferon alpha-4 is a protein that in humans is encoded by the IFNA4 gene. References ^ a b c GRCh38: Ensembl release 89 ...

  9. Stimulator of interferon genes - Wikipedia

    en.wikipedia.org/wiki/Stimulator_of_interferon_genes

    Stimulator of interferon genes (STING), also known as transmembrane protein 173 (TMEM173) and MPYS/MITA/ERIS is a protein that in humans is encoded by the STING1 gene. [ 5 ] STING plays an important role in innate immunity .