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AL amyloidosis is caused by the deposition of abnormal antibody free light chains. The abnormal light chains are produced by monoclonal plasma cells, and, although AL amyloidosis can occur without diagnosis of another disorder, it is often associated with other plasma cell disorders, such as multiple myeloma and Waldenström's macroglobulinemia. [6]
Atrial fibrillation (AF, AFib or A-fib) is an abnormal heart rhythm (arrhythmia) characterized by rapid and irregular beating of the atrial chambers of the heart. [ 11 ] [ 12 ] It often begins as short periods of abnormal beating , which become longer or continuous over time. [ 4 ]
This can be due to a damaged bundle branch that is completely unable to conduct, but may represent intact conduction that is slower than normal. LBBB may be fixed, present at all times, but may be intermittent for example occurring only during rapid heart rates. This may be due to the bundle having a longer refractory period than usual. [3]
Atrial fibrillation: Red dots show atrial fibrillation activity. Atrial fibrillation meets the definition of SVT when associated with a ventricular response greater than 100 beats per minute. It is characterized as an "irregularly, irregular rhythm" both in its atrial and ventricular depolarizations and is distinguished by its fibrillatory ...
AFib is most common in people over 50, and the prevalence and associated risk factors such as stroke increase with age. Blood thinners are the most common treatment to lower the risk of stroke in ...
Those who have severe symptoms from an arrhythmia or are medically unstable may receive urgent treatment with a controlled electric shock in the form of cardioversion or defibrillation. [6] Arrhythmia affects millions of people. [4] In Europe and North America, as of 2014, atrial fibrillation affects about 2% to 3% of the population. [9]
People with frequent Afib might undergo a more aggressive treatment call ablation, where doctors burn or freeze that areas of the heart that are contributing to the irregular heartbeat.
Flecainide intoxication is rare but serious due to the cardiogenic shock that it provokes. Its diagnosis can be difficult in the lack of contributing anamnestic elements. Clinical and paraclinical signs are not specific. Treatment is primarily symptomatic, which gives good results thanks to the hypertonic solution of sodium salts.