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A uterotonic, also known as an oxytocic or ecbolic, is a type of medication used to induce contraction or greater tonicity of the uterus. Uterotonics are used both to induce labor and to reduce postpartum hemorrhage. [1] Labor induction in the third trimester of pregnancy may be required due to medical necessity, or may be desired for social ...
Intravenous or intramuscular oxytocin is the drug of choice for postpartum hemorrhage. [19] [20] Ergotamine may also be used. [2] Oxytocin helps the uterus to contract quickly and the contractions to last longer. [21] It is the first line treatment for PPH when its cause is the uterus not contracting well. [22]
Other definitions of excessive postpartum bleeding are hemodynamic instability, drop of hemoglobin of more than 10%, [12] or requiring blood transfusion. In the literature, primary postpartum hemorrhage is defined as uncontrolled bleeding that occurs in the first 24 hours after delivery while secondary hemorrhage occurs between 24 hours and six ...
Uterine balloon tamponade (UBT) is a non-surgical method of treating refractory postpartum hemorrhage.Once postpartum hemorrhage has been identified and medical management given (including agents such as uterotonics and tranexamic acid), UBT may be employed to tamponade uterine bleeding without the need to pursue operative intervention.
Therefore, a lack of uterine muscle contraction can lead to an acute hemorrhage, as the vasculature is not being sufficiently compressed. [1] Uterine atony is the most common cause of postpartum hemorrhage, which is an emergency and potential cause of fatality. Across the globe, postpartum hemorrhage is among the top five causes of maternal ...
A retained placenta is commonly a cause of postpartum haemorrhage, both primary and secondary. [1] Retained placenta is generally defined as a placenta that has not undergone placental expulsion within 30 minutes of the baby’s birth where the third stage of labor has been managed actively. [2]
Administration is performed immediately following parturition to minimize risk of postpartum hemorrhage by inducing uterine contractions, increasing muscle tone and thickening the blood. If further uterine stimulation is needed, treatment with other forms of oxytocic uterotonic drugs should be used. [17]
Ergonovine, also known as ergometrine and lysergic acid propanolamide is a medication used to cause contractions of the uterus to treat heavy vaginal bleeding after childbirth. [ 6 ] [ 1 ] It can be used either by mouth, by injection into a muscle , or injection into a vein . [ 6 ]