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  2. Immunoglobulin G - Wikipedia

    en.wikipedia.org/wiki/Immunoglobulin_G

    IgG is the main type of antibody found in blood and extracellular fluid, allowing it to control infection of body tissues. By binding many kinds of pathogens such as viruses, bacteria, and fungi, IgG protects the body from infection. [citation needed] It does this through several mechanisms: [citation needed]

  3. Anti-tetanus immunoglobulin - Wikipedia

    en.wikipedia.org/wiki/Anti-tetanus_immunoglobulin

    The immunoglobulin is categorized as immunoglobulin G (IgG). [4] Since the tetanus toxin permanently binds to human tissues, only unbounded molecules can be neutralized by the immunoglobulin. [2] Use of the horse version became common in the 1910s, while the human version came into frequent use in the 1960s. [6]

  4. Antibody - Wikipedia

    en.wikipedia.org/wiki/Antibody

    Each antibody binds to a specific antigen in a highly specific interaction analogous to a lock and key.. An antibody (Ab) or immunoglobulin (Ig) is a large, Y-shaped protein belonging to the immunoglobulin superfamily which is used by the immune system to identify and neutralize antigens such as bacteria and viruses, including those that cause disease.

  5. Immunoglobulin therapy - Wikipedia

    en.wikipedia.org/wiki/Immunoglobulin_therapy

    Immunoglobulin therapy is the use of a mixture of antibodies (normal human immunoglobulin) to treat several health conditions. [13] [14] These conditions include primary immunodeficiency, immune thrombocytopenic purpura, chronic inflammatory demyelinating polyneuropathy, Kawasaki disease, certain cases of HIV/AIDS and measles, Guillain–Barré syndrome, and certain other infections when a ...

  6. Monoclonal antibody therapy - Wikipedia

    en.wikipedia.org/wiki/Monoclonal_antibody_therapy

    Murine antibodies in vitro are thereby transformed into fully human antibodies. [3] The heavy and light chains of human IgG proteins are expressed in structural polymorphic (allotypic) forms. Human IgG allotype is one of the many factors that can contribute to immunogenicity. [16] [17]

  7. Immune system - Wikipedia

    en.wikipedia.org/wiki/Immune_system

    Helper T cells regulate both the innate and adaptive immune responses and help determine which immune responses the body makes to a particular pathogen. [66] [67] These cells have no cytotoxic activity and do not kill infected cells or clear pathogens directly. They instead control the immune response by directing other cells to perform these ...

  8. CD4 immunoadhesin - Wikipedia

    en.wikipedia.org/wiki/CD4_immunoadhesin

    CD4 immunoadhesin was first developed in the mid-1990s as a potential therapeutic agent and treatment for HIV/AIDS. The protein is a fusion of the extracellular domain of the CD4 receptor and the Fc domain of human immunoglobulin G (IgG), the most abundant antibody isotype in the human body. [1]

  9. Polyclonal antibodies - Wikipedia

    en.wikipedia.org/wiki/Polyclonal_antibodies

    Antibodies are currently also being produced from isolation of human B-lymphocytes to produce specific recombinant monoclonal antibody mixtures. The biotechnology company, Symphogen, develops this type of antibodies for therapeutic applications. They are the first research company to reach phase two trials with the monoclonal antibody mixtures ...

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