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  2. Acute uric acid nephropathy - Wikipedia

    en.wikipedia.org/wiki/Acute_uric_acid_nephropathy

    Acute uric acid nephropathy is caused by deposition of uric acid crystals within the kidney interstitium and tubules, leading to partial or complete obstruction of collecting ducts, renal pelvis, or ureter. This obstruction is usually bilateral, and patients follow the clinical course of acute kidney failure.

  3. Gout - Wikipedia

    en.wikipedia.org/wiki/Gout

    Gout presenting as slight redness in the metatarsophalangeal joint of the big toe. Gout can present in several ways, although the most common is a recurrent attack of acute inflammatory arthritis (a red, tender, hot, swollen joint). [4] The metatarsophalangeal joint at the base of the big toe is affected most often, accounting for half of cases ...

  4. Lesch–Nyhan syndrome - Wikipedia

    en.wikipedia.org/wiki/Lesch–Nyhan_syndrome

    The drug allopurinol is utilized to stop the conversion of oxypurines into uric acid, and prevent the development of subsequent arthritic tophi (produced after having chronic gout), kidney stones, and nephropathy, the resulting kidney disease. Allopurinol is taken orally, at a typical dose of 3–20 mg/kg per day.

  5. Uricosuric - Wikipedia

    en.wikipedia.org/wiki/Uricosuric

    URAT1 is the central mediator in the transport of uric acid from the kidney into the blood. In some persons with loss-of-function mutations of URAT1, the uricosurics benzbromarone and losartan had no effect, suggesting these drugs act on URAT1 in vivo. [1] Thus, uricosuric drugs may be candidates for management in a personalized medicine model.

  6. Uric acid - Wikipedia

    en.wikipedia.org/wiki/Uric_acid

    An individual can have serum values as high as 96 mg/L and not have gout. [18] In humans, about 70% of daily uric acid disposal occurs via the kidneys, and in 5–25% of humans, impaired renal (kidney) excretion leads to hyperuricemia. [19]

  7. Hypouricemia - Wikipedia

    en.wikipedia.org/wiki/Hypouricemia

    Hypouricemia is often benign and not a medical condition, but it is a useful medical sign. It is known occasionally to result in a decreased ability to concentrate urine due to decreased hypertonicity of the renal medulla, and may contribute to hypotension when other risk factors are present.

  8. List of ICD-9 codes 240–279: endocrine, nutritional and ...

    en.wikipedia.org/wiki/List_of_ICD-9_codes_240...

    This is a shortened version of the third chapter of the ICD-9: Endocrine, Nutritional and Metabolic Diseases, and Immunity Disorders.It covers ICD codes 240 to 279.The full chapter can be found on pages 145 to 165 of Volume 1, which contains all (sub)categories of the ICD-9.

  9. Rhabdomyolysis - Wikipedia

    en.wikipedia.org/wiki/Rhabdomyolysis

    Rhabdomyolysis complicated by acute kidney impairment in patients with traumatic injury may have a mortality rate of 20%. [4] Admission to the intensive care unit is associated with a mortality of 22% in the absence of acute kidney injury, and 59% if kidney impairment occurs. [ 10 ]

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