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The lamina propria is a loose connective tissue, hence it is not as fibrous as the underlying connective tissue of the submucosa. [4] [self-published source?] The connective tissue and architecture of the lamina propria is very compressible and elastic, this can be seen in organs that require expansion such as the bladder. [5]
Vaginal rugae disappear in older women and those with an estrogen deficiency. [7] The rugae can disappear with anterior vaginal wall prolapse which can occur when supports to the portion located between the vagina and bladder are damaged and the bladder bulges into the vaginal lumen.
Below the epithelium sits the lamina propria. The lamina propria is made up of loose connective tissue with many elastic fibers interspersed with blood vessels, veins and lymphatics. The ureter is surrounded by two muscular layers, an inner longitudinal layer of muscle, and an outer circular or spiral layer of muscle.
In women, childbirth, obesity, and age can all be risk factors, especially by weakening the pelvic floor muscles. [6] In men, prostate surgery (prostatectomy, TURP, etc) and radiation therapy can damage the sphincter and cause stress incontinence. [7] Neurogenic bladder dysfunction can involve a malfunctioning urethral sphincter. [8]
Bladder location and associated structures in the male. In males, the prostate gland lies outside the opening for the urethra. The middle lobe of the prostate causes an elevation in the mucous membrane behind the internal urethral orifice called the uvula of urinary bladder. The uvula can enlarge when the prostate becomes enlarged.
Among women with chronic pelvic pain, the most common comorbidities are endometriosis (70%), postpartum pelvic pain (44%), bladder pain syndrome (61%) and irritable bowel syndrome (39%).
The mucosa is composed of one or more layers of epithelial cells that secrete mucus, and an underlying lamina propria of loose connective tissue. [1] The type of cells and type of mucus secreted vary from organ to organ and each can differ along a given tract. [2] [3]
The pelvic cavity also contains major arteries, veins, muscles, and nerves. These structures coexist in a crowded space, and disorders of one pelvic component may impact upon another; for example, constipation may overload the rectum and compress the urinary bladder, or childbirth might damage the pudendal nerves and later lead to anal weakness.