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Because clonazepam is effective in low milligram doses (0.5 mg clonazepam = 10 mg diazepam), [118] [119] it is said to be among the class of "highly potent" benzodiazepines. [120] The anticonvulsant properties of benzodiazepines are due to the enhancement of synaptic GABA responses, and the inhibition of sustained, high-frequency repetitive firing.
[62] [63] Benzodiazepine has several risks based on its biochemical function and symptoms associated with this medication like exacerbation of sleep apnea, sedation, suppression of self-care functions, amnesia and disinhibition are suggested as a possible explanation to the increase in mortality. Studies also demonstrate that an increased ...
It is preferred that benzodiazepines be taken intermittently and at the lowest effective dose. They improve sleep-related problems by shortening the time spent in bed before falling asleep, prolonging the sleep time, and, in general, reducing wakefulness. [42] [43] However, they worsen sleep quality by increasing light sleep and decreasing deep ...
In addition to treating anxiety and seizures, clonazepam also has off-label uses for restless leg syndrome, acute mania, insomnia and the neurological condition tardive dyskinesia, which causes ...
Additional packages of clonazepam, a prescription medication used to treat seizures and anxiety, mislabeled with the incorrect strength have been added to a voluntary recall, according to the U.S ...
Sleep apnea. Severe liver diseases such as cirrhosis and hepatitis. [19] Severe respiratory failure. Benzodiazepines require special precaution if used in the elderly, during pregnancy, in children, alcohol or drug-dependent individuals, and individuals with comorbid psychiatric disorders. [20]
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