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Vitamin A status involves eye health via two separate functions. Retinal is an essential factor in rod cells and cone cells in the retina responding to light exposure by sending nerve signals to the brain. An early sign of vitamin A deficiency is night blindness. [6] Vitamin A in the form of retinoic acid is essential to normal epithelial cell ...
Estimates are that each year there are 350,000 cases of childhood blindness due to vitamin A deficiency. [5] The causes are vitamin A deficiency during pregnancy, followed by low transfer of vitamin A during lactation and infant/child diets low in vitamin A or beta-carotene.
Nyctalopia (/ ˌ n ɪ k t ə ˈ l oʊ p i ə /; from Ancient Greek νύκτ-(núkt-) 'night' ἀλαός (alaós) 'blind, invisible' and ὄψ (óps) 'eye'), [1] also called night-blindness, is a condition making it difficult or impossible to see in relatively low light. It is a symptom of several eye diseases.
Vitamin A supplementation of children under five who are at risk of VAD has been found to reduce all‐cause mortality by 12 to 24%. [30] Side effects of vitamin A supplements are rare. Vitamin A toxicity is a rare concern associated with high levels of vitamin A over prolonged periods of time.
Retinol, also called vitamin A 1, is a fat-soluble vitamin in the vitamin A family that is found in food and used as a dietary supplement. [3] Retinol or other forms of vitamin A are needed for vision, cellular development, maintenance of skin and mucous membranes , immune function and reproductive development. [ 3 ]
Vitamin A deficiency is a leading cause of preventable childhood blindness, particularly in developing countries. Vitamin A deficiency is defined as a serum (blood) concentration of less than 0.70 μmol/L while a severe deficiency is defined as less than 0.35 μmol/L, per the Centers of Disease Control National Health and Nutrition Examination ...
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Night blindness is especially prominent in developing countries due to malnutrition and therefore a lack of vitamin A in the diet. [55] In developed countries night blindness has historically been uncommon due to adequate food availability; however, the incidence is expected to increase as obesity becomes more common.