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  2. Cas12a - Wikipedia

    en.wikipedia.org/wiki/Cas12a

    Like other Cas enzymes, Cas12a binds to a "guide" RNA (termed a crRNA, or CRISPR RNA) which targets it to a DNA sequence in a specific and programmable matter. In the host organism, the crRNA contains a constant region that is recognized by the Cas12a protein and a "spacer" region that is complementary to a piece of foreign nucleic acid (e.g. a ...

  3. CRISPR activation - Wikipedia

    en.wikipedia.org/wiki/CRISPR_activation

    See: Guide RNA, CRISPR. Complementary base pairing between the sgRNA and genomic DNA allows targeting of Cas9 or dCas9. A small guide RNA (sgRNA), or gRNA is an RNA with around 20 nucleotides used to direct Cas9 or dCas9 to their targets. gRNAs contain two major regions of importance for CRISPR systems: the scaffold and spacer regions.

  4. CRISPR-associated transposons - Wikipedia

    en.wikipedia.org/wiki/CRISPR-associated_transposons

    CRISPR-associated transposons or CASTs are mobile genetic elements that have evolved to make use of minimal CRISPR systems for RNA-guided transposition of their DNA. [1] Unlike traditional CRISPR systems that contain interference mechanisms to degrade targeted DNA, CASTs lack proteins and/or protein domains responsible for DNA cleavage. [ 2 ]

  5. iPhone 12 - Wikipedia

    en.wikipedia.org/wiki/IPhone_12

    The iPhone 12 features a 6.1-inch (155 mm) display [33] with Super Retina XDR OLED technology at a resolution of 2532 × 1170 pixels and a pixel density of about 460 ppi. [34] The iPhone 12 Mini features a 5.4-inch (137 mm) display with the same technology at a resolution of 2340 × 1080 pixels, and a pixel density of about 476 ppi.

  6. Off-target genome editing - Wikipedia

    en.wikipedia.org/wiki/Off-target_genome_editing

    Off-target genome editing refers to nonspecific and unintended genetic modifications that can arise through the use of engineered nuclease technologies such as: clustered, regularly interspaced, short palindromic repeats ()-Cas9, transcription activator-like effector nucleases (), meganucleases, and zinc finger nucleases (ZFN). [1]

  7. 3 Things You Need to Know if You Buy CRISPR ... - AOL

    www.aol.com/3-things-know-buy-crispr-144500442.html

    CRSP Market Cap data by YCharts. 3. Intensive competition. The success of CRISPR Therapeutics will depend on its ability to bring multiple new drugs to the market to support a more viable business ...

  8. List of iPhone models - Wikipedia

    en.wikipedia.org/wiki/List_of_iPhone_models

    The iPhone, developed by Apple Inc., is a line of smartphones that combine a mobile phone, digital camera, personal computer, and music player into one device. Introduced by then-CEO Steve Jobs on January 9, 2007, the iPhone revolutionized the mobile phone industry with its multi-touch interface and lack of physical keyboard.

  9. CRISPR - Wikipedia

    en.wikipedia.org/wiki/CRISPR

    Cas9 (or "CRISPR-associated protein 9") is an enzyme that uses CRISPR sequences as a guide to recognize and open up specific strands of DNA that are complementary to the CRISPR sequence. Cas9 enzymes together with CRISPR sequences form the basis of a technology known as CRISPR-Cas9 that can be used to edit genes within living organisms.

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