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  2. Modified-release dosage - Wikipedia

    en.wikipedia.org/wiki/Modified-release_dosage

    Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release [ER, XR, XL] dosage) or to a specific target in the body (targeted-release dosage). [1] Sustained-release dosage forms are dosage ...

  3. Stimuli-responsive drug delivery systems - Wikipedia

    en.wikipedia.org/wiki/Stimuli-responsive_drug...

    He first introduced the idea of a prolonged drug release system as a means of constant rate delivery while experimenting with anesthetic gases and arterio-venous shunts on mice [4] This inspired the formation of a company called ALZA by a chemist named Alejandro Zaffaroni, whose primary focus was on the development of drug carrying systems that ...

  4. Extended-release morphine - Wikipedia

    en.wikipedia.org/wiki/Extended-release_morphine

    Extended-release (or slow-release) formulations of morphine are those whose effect last substantially longer than bare morphine, availing for, e.g., one administration per day. Conversion between extended-release and immediate-release (or "regular") morphine is easier than conversion to or from an equianalgesic dose of another opioid with ...

  5. Pharmaceutical formulation - Wikipedia

    en.wikipedia.org/wiki/Pharmaceutical_formulation

    In other sustained release formulations the matrix swells to form a gel through which the drug exits. Another method by which sustained release is achieved is through an osmotic controlled-release oral delivery system, where the active compound is encased in a water-permeable membrane with a laser drilled hole at one end. As water passes ...

  6. Bupropion - Wikipedia

    en.wikipedia.org/wiki/Bupropion

    Sustained-release (SR) and extended-release (XL) formulations have been designed to slow down absorption resulting in t max of 3 hours and 5 hours, respectively. [109] Absolute bioavailability of bupropion is unknown but is presumed to be low, at 5–20%, due to the first-pass metabolism. As for the relative bioavailability of the formulations ...

  7. Simmons would have a significant impact on the Peach Bowl; he was the player who tackled Texas quarterback Quinn Ewers for a crucial third-quarter safety.

  8. Bioavailability - Wikipedia

    en.wikipedia.org/wiki/Bioavailability

    The drug formulation (immediate release, excipients used, manufacturing methods, modified release – delayed release, extended release, sustained release, etc.) Whether the formulation is administered in a fed or fasted state; Gastric emptying rate; Circadian differences; Interactions with other drugs/foods:

  9. Nordstrom's extended Cyber Monday sale has all new ... - AOL

    www.aol.com/lifestyle/nordstroms-extended-cyber...

    In a delightful turn of events, they've extended some of the Cyber Monday savings. It's not just already on-sale styles remaining; somehow, Nordstrom's found new markdowns just added, with up to ...