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Osteoarthritis is the most common form of arthritis, affecting about 237 million people or 3.3% of the world's population, as of 2015. [4] [12] It becomes more common as people age. [1] Among those over 60 years old, about 10% of males and 18% of females are affected. [2] Osteoarthritis is the cause of about 2% of years lived with disability. [12]
The strongest predictor of osteoarthritis is increased age, likely due to the declining ability of chondrocytes to maintain the structural integrity of cartilage. [69] More than 30 percent of women have some degree of osteoarthritis by age 65. Other risk factors for osteoarthritis include prior joint trauma, obesity, and a sedentary lifestyle. [70]
Celecoxib, sold under the brand name Celebrex among others, is a COX-2 inhibitor and nonsteroidal anti-inflammatory drug (NSAID). [7] It is used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis. [7]
Levothyroxine is a frequently prescribed drug in the United States, particularly for older people, as lower thyroid function can be associated with aging. Questions remain over how appropriately ...
1. Pancreatitis. Pancreatitis (inflammation of the pancreas) was reported in clinical trials on Ozempic. But the results weren’t conclusive. If pancreatitis is indeed a risk, it seems to be ...
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CMC OA is the most common form of OA affecting the hand. [37] Dahaghin et al. showed that about 15% of women and 7% of men between 50 and 60 years of age develop CMC OA of the thumb. [38] However, in about 65% of people older than 55 years, radiologic evidence of OA was present without any symptoms. [38]
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