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Acanthocyte (from the Greek word ἄκανθα acantha, meaning 'thorn'), in biology and medicine, refers to an abnormal form of red blood cell that has a spiked cell membrane, due to thorny projections. [1] [2] A similar term is spur cells. Often they may be confused with echinocytes or schistocytes.
Reference ranges (reference intervals) for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples. Reference ranges for blood tests are studied within the field of clinical chemistry (also known as "clinical biochemistry", "chemical pathology" or "pure blood chemistry"), the ...
The mean corpuscular hemoglobin, or "mean cell hemoglobin" (MCH), is the average mass of hemoglobin (Hb) per red blood cell (RBC) in a sample of blood. It is reported as part of a standard complete blood count. MCH value is diminished in hypochromic anemias. [1] RBCs are either normochromic or hypochromic. They are never "hyperchromic".
Crenation is also used to describe a feature of red blood cells. These erythrocytes look as if they have projections extending from a smaller central area, like a spiked ball. The crenations may be either large, irregular spicules of acanthocytes, or smaller, more numerous, regularly irregular projections of echinocytes. [3]
Red blood cell indices are blood tests that provide information about the hemoglobin content and size of red blood cells. Abnormal values indicate the presence of anemia and which type of anemia it is.
Hemoglobin is an iron-containing protein that gives red blood cells their color and facilitates transportation of oxygen from the lungs to tissues and carbon dioxide from tissues to the lungs to be exhaled. [3] Red blood cells are the most abundant cell in the blood, accounting for about 40-45% of its volume.
This leads to a markedly decreased red blood cell count and hematocrit and markedly elevated mean cell volume and mean cell hemoglobin concentration. [ 5 ] : 32–3 Red cell agglutination also interferes with routine methods for blood typing and blood compatibility testing , which rely on agglutination reactions.
This is an incomplete list, which may never be able to satisfy certain standards for completion.. There are many conditions of or affecting the human hematologic system—the biological system that includes plasma, platelets, leukocytes, and erythrocytes, the major components of blood and the bone marrow.