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Opioids are not recommended for treatment of acute migraines due to their significant side effect profile, including twice the risk of medication overuse headache when compared to NSAIDS, acetaminophen or triptans. [3] In addition, their strength of efficacy has showed to be low or insufficient for pain relief of migraines. [3]
[12] [13] Aspirin (900 to 1000 mg) can relieve moderate to severe migraine pain, with an effectiveness similar to sumatriptan. [14] [15] Paracetamol, either alone or in combination with metoclopramide (an anti-nausea drug), is an effective treatment with a low risk of adverse effects.
In the United Kingdom, prochlorperazine is available for the treatment of nausea caused by migraine as a tablet dissolved in the mouth, and in Australia as a tablet swallowed whole. In the UK, it is available via a prescription and as a pharmacy medicine , meaning it does not require a prescription but is only available after talking with a ...
The pain needs to last at least for at least 4 hours without medication and it needs to meet two out of four criteria: ... sensitivity to light or nausea to be diagnosed with migraine, Singh says ...
Initial recommended treatment for acute attacks is with over-the-counter analgesics (pain medication) such as ibuprofen and paracetamol (acetaminophen) for headache, antiemetics (anti-nausea medication) for nausea, and the avoidance of migraine triggers. [13]
Sumatriptan is effective for ending or relieving the intensity of migraine and cluster headaches. [9] It is most effective when taken early after the start of the pain. [9] Injected sumatriptan is more effective than other formulations. [10] Oral sumatriptan can be used also in the treatment of post-dural puncture headache. [11]
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