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A Howell–Jolly body (marked by arrow) within an erythrocyte. A Howell–Jolly body is a cytopathological finding of basophilic nuclear remnants (clusters of DNA) in circulating erythrocytes. During maturation in the bone marrow, late erythroblasts normally expel their nuclei; but, in some cases, a small portion of DNA remains. The presence of ...
Blood smear showing red blood cells with basophilic stippling. Basophilic stippling, also known as punctate basophilia, is the presence of numerous basophilic granules that are dispersed through the cytoplasm of erythrocytes in a peripheral blood smear.
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Howell-Jolly body-like inclusions (HJBLi) are a hematopathological finding of an inclusion arising from detached DNA nuclear fragment in white blood cells caused by dysplastic granulopoiesis. [1] The inclusion is aptly named for its similar appearance of the Howell–Jolly body in erythrocytes. [2] The term was coined in 1989. [2]
Döhle bodies are light blue-gray, oval, basophilic, leukocyte inclusions located in the peripheral cytoplasm of neutrophils.They measure 1–3 μm in diameter. Not much is known about their formation, but they are thought to be remnants of the rough endoplasmic reticulum.
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Acanthocytes, from peripheral blood, under light microscopy. Note the irregularly shaped, non-circular cells in the image. Acanthocyte (from the Greek word ἄκανθα acantha, meaning 'thorn'), in biology and medicine, refers to an abnormal form of red blood cell that has a spiked cell membrane, due to thorny projections.
Theodor Boveri originally observed the fact that abnormal nuclear morphologies commonly occur in cancer.Micronuclei are also referred to Howell-Jolly bodies; discovered by hematologists William Henry Howell and Justin Marie Jolly in erythrocytes.