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A biosafety level (BSL), or pathogen/protection level, is a set of biocontainment precautions required to isolate dangerous biological agents in an enclosed laboratory facility. The levels of containment range from the lowest biosafety level 1 (BSL-1) to the highest at level 4 (BSL-4).
The United States Centers for Disease Control and Prevention (CDC) categorizes various diseases in levels of biohazard, Level 1 being minimum risk and Level 4 being extreme risk. Laboratories and other facilities are categorized as BSL (Biosafety Level) 1–4 or as P1 through P4 for short (Pathogen or Protection Level). [citation needed]
The Department of Health and Human Services (HHS) lists are located at 42 CFR Part 73.3 [2] and 42 CFR Part 73.4. [3] The USDA animal safety list is located at 9 CFR Subchapter B. [ 4 ] Not all select agents require BSL-4 handling, namely select bacteria and toxins, but most select agent viruses do (with the notable exception of SARS-CoV-1 ...
The levels of containment range from the lowest biosafety level 1 (BSL-1) to the highest at level 4 (BSL-4). In the United States, the Centers for Disease Control and Prevention (CDC) have specified these levels. [8] In the European Union, the same biosafety levels are defined in a directive. [9]
Laboratories are assigned a biosafety level numbered 1 through 4 based on their potential biohazard risk level. [8] The employing authority, through the laboratory director, is responsible for ensuring that there is adequate surveillance of the health of laboratory personnel. [ 9 ]
NEIDL is one of only 13 operational or planned biosafety level 4 (BSL-4) laboratories in the United States. NEIDL's current director is Nancy Sullivan, ScD . She previously served as the chief of the Biosecurity Research Section at the Vaccine Research Center of the National Institute of Allergy and Infectious Diseases (NIAID) in the National ...
NBACC laboratories operate at the biosafety levels of 2, 3, and 4, providing the optimal level of safety and operational capacity. In particular, the NBACC's biosafety level of 4 allows its facilities to research pathogens that have no existing vaccines or treatment. This makes it one of only seven locations in the United States where this ...
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