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Biosafety level 4 laboratories are designed for diagnostic work and research on easily respiratory-acquired viruses which can often cause severe and/or fatal disease. What follows is a list of select agents that have specific biocontainment requirements according to US federal law.
A biosafety level (BSL), or pathogen/protection level, is a set of biocontainment precautions required to isolate dangerous biological agents in an enclosed laboratory facility. The levels of containment range from the lowest biosafety level 1 (BSL-1) to the highest at level 4 (BSL-4).
The United States Centers for Disease Control and Prevention (CDC) categorizes various diseases in levels of biohazard, Level 1 being minimum risk and Level 4 being extreme risk. Laboratories and other facilities are categorized as BSL (Biosafety Level) 1–4 or as P1 through P4 for short (Pathogen or Protection Level). [citation needed]
The levels of containment range from the lowest biosafety level 1 (BSL-1) to the highest at level 4 (BSL-4). In the United States, the Centers for Disease Control and Prevention (CDC) have specified these levels. [8] In the European Union, the same biosafety levels are defined in a directive. [9]
The NBTCC has unique national biosafety level 3 and 4 aerobiology capabilities, which are necessary to collect crucial data that is used to develop biodefense plans and responses. In 2013, it provided necessary data, which addressed 10 specific biological agent knowledge gaps, to improve hazard, risk, and threat assessments.
USAMRIID is the only laboratory of the United States Department of Defense (DoD) equipped to study highly hazardous viruses at Biosafety Level 4 within positive pressure personnel suits. USAMRIID employs both military and civilian scientists as well as highly specialized support personnel, totaling around 800 people.
NEIDL is one of only 13 operational or planned biosafety level 4 (BSL-4) laboratories in the United States. NEIDL's current director is Nancy Sullivan, ScD . She previously served as the chief of the Biosecurity Research Section at the Vaccine Research Center of the National Institute of Allergy and Infectious Diseases (NIAID) in the National ...
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