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Cellular hypertrophy is an increase in cell size and volume. If enough cells of an organ hypertrophy the whole organ will increase in size. Hypertrophy may involve an increase in intracellular protein as well as cytosol (intracellular fluid) and other cytoplasmic components.
Other health problems compound the chronic complications of diabetes such as smoking, obesity, high blood pressure, elevated cholesterol levels, and lack of regular exercise. Complications of diabetes are a strong risk factor for severe COVID-19 illness. [6]
Multiple organ dysfunction syndrome (MODS) is altered organ function in an acutely ill patient requiring immediate medical intervention. [1]There are different stages of organ dysfunction for certain different organs, both in acute and in chronic onset, whether or not there are one or more organs affected.
The use of indicators in diagnosing alterations in spiritual health is controversial because indicators may appear related to both spiritual and psychosocial problems. Wilfred McSherry, a senior lecturer in the School of Care Sciences at the University of Glamorgan , published an article on the Journal of Advanced Nursing about potential ...
AEIOU-TIPS is a mnemonic acronym used by some medical professionals to recall the possible causes for altered mental status.Medical literature discusses its utility in determining differential diagnoses in various special populations presenting with altered mental status including infants, [1] children, [2] adolescents, [3] and the elderly. [4]
Alterations in the genetic code have long been considered one of the main causal factors in aging. [4] [5] In multicellular organisms genome instability is central to carcinogenesis, [6] and in humans it is also a factor in some neurodegenerative diseases such as amyotrophic lateral sclerosis or the neuromuscular disease myotonic dystrophy.
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Epigenetic alterations of gene expression are closely related with developmental origins of the health and disease hypothesis. DNA methylation, histone modifications and non-coding RNAs are altered by the environment in the womb and potentially go on to produce higher rates of adult disease later in life.