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Trials in emergency department settings support the use of ondansetron to abort vomiting episodes associated with gastroenteritis and dehydration. [20] A randomized controlled trial using a single dose of oral ondansetron in children with presumably viral gastroenteritis found it to be highly effective in stopping vomiting and increasing the effectiveness of oral rehydration therapy, thereby ...
Ondansetron (Zofran) is administered in an oral tablet form, orally dissolving tablet form, orally dissolving film, sublingual, or in an IV/IM injection. Tropisetron ( Setrovel, Navoban ) can be administered in oral capsules or in injection form.
Ondansetron was approved by the U.S. Food and Drug Administration in 1991, and has since become available in several other countries, including the UK, Ireland, Australia, Canada, France and Brazil. As of 2008, ondansetron and granisetron are the only 5-HT 3 antagonists available as a generic drug in the United States. Ondansetron may be given ...
Take Zofran. If you know you’re prone to motion sickness and vomiting from motion sickness, your doctor might prescribe ondansetron, also known as Zofran. It comes in a pill and liquid form ...
There is no known safe dose of cannabis while pregnant and use of cannabis may lead to birth defects, pre-term birth, or low birth weight. [80] Tetrahydrocannabinol (THC) , an active ingredient in cannabis, can both cross the placenta and accumulates in high concentrations in breast milk. [ 81 ]
In cases of gastroenteritis, serotonin antagonists such as ondansetron were found to suppress nausea and vomiting, as well as reduce the need for IV fluid resuscitation. [22] The combination of pyridoxine and doxylamine is the first line treatment for pregnancy-related nausea and vomiting. [22]
Ondansetron has some utility, with a single dose being associated with less need for intravenous fluids, fewer hospitalizations, and decreased vomiting. [55] [66] [67] [68] Metoclopramide might also be helpful. [68] However, the use of ondansetron might possibly be linked to an increased rate of return to hospital in children. [69]
After surviving an assassination attempt in the Tucson mass shooting last January, Rep. Gabrielle Giffords (D) resigned from Congress in January 2012. In the June special election, Jesse Kelly (R) — an Iraq War veteran who lost to Giffords in 2010 — was defeated by Ron Barber (D), Giffords' district director who was also wounded in Tucson.