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  2. Founder effect - Wikipedia

    en.wikipedia.org/wiki/Founder_effect

    In humans, founder effects can arise from cultural isolation, and inevitably, endogamy. For example, the Amish populations in the United States exhibit founder effects because they have grown from a very few founders, have not recruited newcomers, and tend to marry within the community.

  3. Population bottleneck - Wikipedia

    en.wikipedia.org/wiki/Population_bottleneck

    Population bottleneck followed by recovery or extinction. A population bottleneck or genetic bottleneck is a sharp reduction in the size of a population due to environmental events such as famines, earthquakes, floods, fires, disease, and droughts; or human activities such as genocide, speciocide, widespread violence or intentional culling.

  4. Genetic drift - Wikipedia

    en.wikipedia.org/wiki/Genetic_drift

    The founder effect is a special case of a population bottleneck, occurring when a small group in a population splinters off from the original population and forms a new one. The random sample of alleles in the just formed new colony is expected to grossly misrepresent the original population in at least some respects. [44]

  5. Recent African origin of modern humans - Wikipedia

    en.wikipedia.org/wiki/Recent_African_origin_of...

    Alternatively, a small European founder population that had expressed haplogroup M and N at first, could have lost haplogroup M through random genetic drift resulting from a bottleneck (i.e. a founder effect). The group that crossed the Red Sea travelled along the coastal route around Arabia and Persia until reaching India. [59]

  6. Human evolution - Wikipedia

    en.wikipedia.org/wiki/Human_evolution

    Human evolution is the ... Distinctive human genetic variability has arisen as the result of the founder effect, ... As a side effect, it allowed human ancestors to ...

  7. Human genetic variation - Wikipedia

    en.wikipedia.org/wiki/Human_genetic_variation

    Human genetic variation is the genetic differences in and ... the so-called founder effect occurs when founder populations bring only a subset of the genetic ...

  8. Ellis–Van Creveld syndrome - Wikipedia

    en.wikipedia.org/wiki/Ellis–van_Creveld_syndrome

    Ellis–Van Creveld syndrome often is the result of founder effects in isolated human populations, such as the Amish and some small island inhabitants. Although relatively rare, this disorder does occur with higher incidence within founder-effect populations due to lack of genetic variability.

  9. Medical genetics of Jews - Wikipedia

    en.wikipedia.org/wiki/Medical_genetics_of_Jews

    Because of a founder effect, the ancestors of present-day Ashkenazi Jews may have kept the low-frequency G2019S mutation through the different diasporas, whereas Near Eastern daughter populations lost the mutation. The mutation might then have been "reintroduced by recurrent gene flow from Ashkenazi populations to other Jewish, European, and ...