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Tizanidine, sold under the brand name Zanaflex among others, is an alpha-2 (α 2) adrenergic receptor agonist, [2] similar to clonidine, that is used to treat muscle spasticity due to spinal cord injury, multiple sclerosis, and spastic cerebral palsy. [3] Effectiveness appears similar to baclofen or diazepam. [4] It is taken by mouth. [5]
A majority of the prophylactic medications work by inhibiting or increasing neurotransmissions in the brain, often preventing the brain from interpreting pain signals. [14] Preventive medicines include CGRP receptor antagonists, gabapentin (Neurontin), tizanidine (Zanaflex), fluoxetine (Prozac), amitriptyline (Elavil), and topiramate (Topamax ...
Muscle relaxants are thought to be useful in painful disorders based on the theory that pain induces spasm and spasm causes pain. However, considerable evidence contradicts this theory. [17] In general, muscle relaxants are not approved by FDA for long-term use.
Several medicines, including tolperisone, aceclofenac plus tizanidine, and pregabalin, are effective in reducing pain intensity. Another comparative study found that eperisone with diclofenac was more effective in terms of finger-floor distance and improvement in Lasegue's sign (straight leg raise angle laying on back), VAS score, and global ...
A number of other medications — including anti-seizure drugs, Botox, muscle relaxers like tizanidine and anti-anxiety or sedative medications like Valium — are used to reduce stiffness on a ...
Applicable conditions include acute back [8] or neck pain, or pain after an injury. Long-term use of muscle relaxants in such cases is poorly supported. [8] Spasm may also be seen in movement disorders featuring spasticity in neurologic conditions such as cerebral palsy, multiple sclerosis, and spinal cord disease. Medications are commonly used ...
The United States Food and Drugs Administration is warning pet owners about a common medication given to pets to treat arthritis. The F.D.A. now says that the drug Librela may be associated with ...
Hollywood is abuzz with allegations of “Ozempic face,” a term for “gaunt” features linked to rapid weight loss. Stars like Katy Perry, Lizzo, and John Goodman are currently facing scrutiny ...
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