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Reproducibility, closely related to replicability and repeatability, is a major principle underpinning the scientific method.For the findings of a study to be reproducible means that results obtained by an experiment or an observational study or in a statistical analysis of a data set should be achieved again with a high degree of reliability when the study is replicated.
Reproducibility can also be distinguished from replication, as referring to reproducing the same results using the same data set. Reproducibility of this type is why many researchers make their data available to others for testing. [15] The replication crisis does not necessarily mean these fields are unscientific.
The Hi-C library also required several days to construct, [4] [8] and the datasets themselves were low in both output and reproducibility. [9] Nevertheless, Hi-C data offered new insights for chromatin conformation as well as nuclear and genomic architectures, and these prospects motivated scientists to put efforts to modify the technique over ...
This glossary of biology terms is a list of definitions of fundamental terms and concepts used in biology, the study of life and of living organisms.It is intended as introductory material for novices; for more specific and technical definitions from sub-disciplines and related fields, see Glossary of cell biology, Glossary of genetics, Glossary of evolutionary biology, Glossary of ecology ...
Biological knowledge is distributed among countless databases. This sometimes makes it difficult to ensure the consistency of information, e.g. when different names are used for the same species or different data formats. As a consequence, inter-operability is a constant challenge for information exchange. For instance, if a DNA sequence ...
In engineering, science, and statistics, replication is the process of repeating a study or experiment under the same or similar conditions. It is a crucial step to test the original claim and confirm or reject the accuracy of results as well as for identifying and correcting the flaws in the original experiment. [1]
Biological data has also been difficult to define, as bioinformatics is a wide-encompassing field. Further, the question of what constitutes as being a living organism has been contentious, as "alive" represents a nebulous term that encompasses molecular evolution, biological modeling, biophysics, and systems biology.
The Reproducibility Project is a series of crowdsourced collaborations aiming to reproduce published scientific studies, finding high rates of results which could not be replicated. It has resulted in two major initiatives focusing on the fields of psychology [ 1 ] and cancer biology. [ 2 ]