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  2. Procainamide - Wikipedia

    en.wikipedia.org/wiki/Procainamide

    There is a close line between the plasma concentrations of the therapeutic and toxic effect, therefore a high risk for toxicity. [12] Many symptoms resemble systemic lupus erythematosus because procainamide reactivates hydroxylamine and nitroso metabolites, which bind to histone proteins and are toxic to lymphocytes .

  3. Disopyramide - Wikipedia

    en.wikipedia.org/wiki/Disopyramide

    In 1972, when it was one of the only alternatives to quinidine, it was praised for being more potent and somewhat less toxic. [6] However, a 2012 review of antiarrhythmic drugs noted that disopyramide is among the most toxic agents, with a high burden of side effects and increased mortality (compared to placebo) when used to treat atrial ...

  4. Dronedarone - Wikipedia

    en.wikipedia.org/wiki/Dronedarone

    Dronedarone has been termed a "multichannel blocker". [citation needed] However, it is unclear which channel(s) play a pivotal role in its success. [9]Thus, dronedarone's actions at the cellular level are controversial, with most studies suggesting an inhibition in multiple outward potassium currents including rapid delayed rectifier, slow delayed rectifier and ACh-activated inward rectifier. [10]

  5. Amiodarone - Wikipedia

    en.wikipedia.org/wiki/Amiodarone

    Amiodarone is an antiarrhythmic medication used to treat and prevent a number of types of cardiac dysrhythmias. [4] This includes ventricular tachycardia, ventricular fibrillation, and wide complex tachycardia, atrial fibrillation, and paroxysmal supraventricular tachycardia. [4]

  6. Flecainide - Wikipedia

    en.wikipedia.org/wiki/Flecainide

    Flecainide is a medication used to prevent and treat abnormally fast heart rates. [1] This includes ventricular and supraventricular tachycardias. [1] Its use is only recommended in those with dangerous arrhythmias or when significant symptoms cannot be managed with other treatments. [1]

  7. 15 Alternatives to Ozempic for Weight Loss - AOL

    www.aol.com/15-alternatives-ozempic-weight-loss...

    Victoza. There are more semaglutide alternatives for weight loss. Victoza is also a GLP-1 receptor agonist, but the active ingredient is liraglutide. Liraglutide works in a similar way to ...

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