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In 1972, when it was one of the only alternatives to quinidine, it was praised for being more potent and somewhat less toxic. [6] However, a 2012 review of antiarrhythmic drugs noted that disopyramide is among the most toxic agents, with a high burden of side effects and increased mortality (compared to placebo) when used to treat atrial ...
Dronedarone has been termed a "multichannel blocker". [citation needed] However, it is unclear which channel(s) play a pivotal role in its success. [9]Thus, dronedarone's actions at the cellular level are controversial, with most studies suggesting an inhibition in multiple outward potassium currents including rapid delayed rectifier, slow delayed rectifier and ACh-activated inward rectifier. [10]
A meta-analysis of various studies in 2015 shown that annual stroke risk is less than 1% in 13 of the 17 studies for CHA 2 DS 2-VASc score of 1, 6 out of 15 studies reported risk of 1 to 2% and 5 out of 15 studies reported risk of more than 2% for CHA 2 DS 2-VASc score of 2. [14]
Atrial fibrillation is linked to a higher risk of stroke and heart attack. It’s not clear what's behind the link. Atrial fibrillation is the most common type of irregular heart rhythm, impacting ...
Amiodarone is an antiarrhythmic medication used to treat and prevent a number of types of cardiac dysrhythmias. [4] This includes ventricular tachycardia, ventricular fibrillation, and wide complex tachycardia, atrial fibrillation, and paroxysmal supraventricular tachycardia. [4]
Atrial fibrillation is the most common clinical arrhythmia worldwide, and nearly one-third of people who undergo cardiac surgery experience it. Potassium, along with other electrolytes, plays an ...
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