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2. Direct factor Xa inhibitors - Wikipedia

   en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

   The monitoring of warfarin and keeping the international normalized ratio (INR) between 2.0 and 3.0, along with avoiding over and under treatment, has driven a search for an alternative. [3] [14] A naturally occurring inhibitor of factor Xa was reported in 1971 by Spellman et al. from the dog hookworm. [15]

3. Rivaroxaban - Wikipedia

   en.wikipedia.org/wiki/Rivaroxaban

   Rivaroxaban, sold under the brand name Xarelto among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. [8] Specifically it is used to treat deep vein thrombosis and pulmonary emboli and prevent blood clots in atrial fibrillation and following hip or knee surgery. [ 8 ]

4. Thrombosis prevention - Wikipedia

   en.wikipedia.org/wiki/Thrombosis_prevention

   Thrombosis prevention or thromboprophylaxis is medical treatment to prevent the development of thrombosis (blood clots inside blood vessels) in those considered at risk for developing thrombosis. [1] Some people are at a higher risk for the formation of blood clots than others, such as those with cancer undergoing a surgical procedure.

5. Discovery and development of direct Xa inhibitors - Wikipedia

   en.wikipedia.org/wiki/Discovery_and_development...

   Rivaroxaban. During the SAR development of rivaroxaban, researchers realized that adding a 5-chlorothiophene-2-carboxamide group to the oxazolidonine core could increase the potency by 200 fold, which had previously been too weak for medical use. In addition to this discovery, a clear preference for the (S)-configuration was confirmed.

6. Ohio corrections officer killed on Christmas Day in 'inmate ...

   www.aol.com/ohio-corrections-officer-killed...

   A corrections officer at an Ohio prison was killed Christmas day when an inmate attacked him, authorities said Wednesday.. The assault occurred Wednesday morning at the Ross Correctional ...

7. Assisted living options for wheelchair users - AOL

   www.aol.com/assisted-living-options-wheelchair...

   Benefits of Assisted Living for Wheelchair Users. Compared to independent living, assisted living can provide a wider breadth of support. These services provide a safe and comfortable atmosphere ...