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Dapagliflozin, sold under the brand names Farxiga (US) and Forxiga (EU) among others, is a medication used to treat type 2 diabetes. [6] [7] [10] It is also used to treat adults with heart failure and chronic kidney disease.
Sotagliflozin (Inpefa) is a dual SGLT1/SGLT2 inhibitor approved by the US Food and Drug Administration (FDA) in May 2023, to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, chronic kidney disease, and other cardiovascular risk factors ...
GLP-1 agonists were developed initially for type 2 diabetes. [5] The 2022 American Diabetes Association (ADA) standards of medical care in diabetes include GLP-1 agonist or SGLT2 inhibitor as a first line pharmacological therapy for type 2 diabetes in patients who have or are at high risk for atherosclerotic cardiovascular disease or heart failure.
The FDA has also approved Ozempic to prevent major cardiovascular events like heart attack or stroke in those with type 2 diabetes ... This includes canagliflozin (Invokana®) and dapagliflozin ...
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Sotagliflozin, sold under the brand name Inpefa among others, is a medication used to reduce the risk of death due to heart failure. [1] It is a sodium-glucose cotransporter 2 (SGLT2) inhibitor. [1] It is taken by mouth. [1] The most common side effect is genital infection in women. [2]
Increase the risk of heart failure; Cause an average of 2–5 kg weight gain; Are associated with a higher risk of edema, anemia and bone fractures; Can increase low-density lipoprotein; Rosiglitazone has been linked to increased triglycerides and an increased risk of a heart attack; Pioglitazone has been linked to an increased risk of bladder ...
Heart failure has historically been irreversible, but a new study suggests that could change. At the University of Utah, scientists used a new gene therapy that reversed heart failure in animals.
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