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  2. Haemophilia - Wikipedia

    en.wikipedia.org/wiki/Haemophilia

    On-demand (or episodic) treatment involves treating bleeding episodes once they arise. In 2007, a trial comparing on-demand treatment of boys (< 30 months) with haemophilia A with prophylactic treatment (infusions of 25 IU/kg body weight of Factor VIII every other day) in respect to its effect on the prevention of joint-diseases.

  3. FDA Approves Pfizer's Second Hemophilia Drug With Six Months

    www.aol.com/fda-approves-pfizers-second...

    Hemophilia is a family of rare genetic blood diseases caused by a clotting factor deficiency (FVIII in hemophilia A, FIX in hemophilia B), impacting more than 800,000 people globally.

  4. Acquired haemophilia - Wikipedia

    en.wikipedia.org/wiki/Acquired_haemophilia

    Acquired haemophilia A (AHA) is a rare but potentially life-threatening bleeding disorder characterized by autoantibodies directed against coagulation factor VIII.These autoantibodies constitute the most common spontaneous inhibitor to any coagulation factor and may induce spontaneous bleeding in patients with no previous history of a bleeding disorder.

  5. Alnylam Presents New Pre-clinical Data on RNAi Therapeutics ...

    www.aol.com/news/2012-12-10-alnylam-presents-new...

    Standard treatment for hemophilia patients involves replacement of the missing clotting factor either as prophylaxis or on-demand therapy. However, as many as one third of hemophilia A patients ...

  6. Haemophilia A - Wikipedia

    en.wikipedia.org/wiki/Haemophilia_A

    Joint capsule. Haemophilia A's phenotype has a quite wide range of symptoms encompassing both internal and external bleeding episodes. Individuals with more severe haemophilia tend to experience more intense and frequent bleeding, whereas those with mild haemophilia typically exhibit milder symptoms unless subjected to surgical procedures or significant trauma.

  7. Regeneron, Intellia Expand Partnership To Develop Hemophilia ...

    www.aol.com/news/regeneron-intellia-expand...

    Regeneron Pharmaceuticals, Inc (REGN) and Intellia Therapeutics, Inc. (NTLA) announced an expansion of their partnership to jointly develop potential products for the treatment of hemophilia A and ...

  8. Haemophilia C - Wikipedia

    en.wikipedia.org/wiki/Haemophilia_C

    In terms of haemophilia C medication tranexamic acid is often used for both treatment after an incident of bleeding and as a preventive measure to avoid excessive bleeding during oral surgery. [ 3 ] Treatment is usually not necessary, except in relation to operations , leading to many of those having the condition not being aware of it.

  9. Concizumab - Wikipedia

    en.wikipedia.org/wiki/Concizumab

    Concizumab, sold under the brand name Alhemo, is a monoclonal antibody used for the treatment of hemophilia A and hemophilia B. [5] [8] It is an anti-tissue factor pathway inhibitor. [5] [8] The most common adverse reactions include injection site reactions and hives (urticaria). [11]

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