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Microbial metabolism is the means by which a microbe obtains the energy and nutrients (e.g. carbon) it needs to live and reproduce.Microbes use many different types of metabolic strategies and species can often be differentiated from each other based on metabolic characteristics.
Desulfovibrio vulgaris is the best-studied sulfate-reducing microorganism species; the bar in the upper right is 0.5 micrometre long.. Sulfate-reducing microorganisms (SRM) or sulfate-reducing prokaryotes (SRP) are a group composed of sulfate-reducing bacteria (SRB) and sulfate-reducing archaea (SRA), both of which can perform anaerobic respiration utilizing sulfate (SO 2−
The Metabolite Set Enrichment Analysis offered by the web server is based on a curated library of more 5000 predefined metabolite sets covering various human metabolic pathways (nearly 100), hundreds of human disease states (in 3 different biofluids), human biofluid and tissue locations as well as human SNP-metabolite associations (4500 ...
A portable embedded system for microbial concentration measurement in liquid and semi-liquid media using impedance microbiology has been recently proposed. [ 16 ] [ 17 ] The system is composed of a thermoregulated incubation chamber where the sample under test is stored and a controller for thermoregulation and impedance measurements.
Major histocompatibility complex class I-related gene protein (MR1) is a non-classical MHC class I protein, that binds vitamine metabolites (intermediates of riboflavin synthesis) produced in certain types of bacteria. MR1 interacts with mucosal associated invariant T cells (MAIT). [5] [6]
Researchers have found that adding a pre-ketone supplement to immunotherapy boosted its effectiveness against prostate cancer in mouse models. Ketone supplement may boost immunotherapy against ...
The synthetic accessibility approach uses the topology of the metabolic network to calculate the sum of the minimum number of steps needed to traverse the metabolic network graph from the inputs, those metabolites available to the organism from the environment, to the outputs, metabolites needed by the organism to survive.
Changing a series of 4-phenoxyquinoline compounds with an acyl thiourea group led to compounds with c-Met activity, e.g. quinoline. [10] This was a key step in the progress of c-Met inhibitor development in that the acyl binding gives the terminal aryl group the ability to penetrate a deep hydrophobic pocket and so it enhances the potency of ...