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Boric acid is applied in a very dilute solution as an eye wash. Boric acid vaginal suppositories can be used for recurrent candidiasis due to non-albicans candida as a second line treatment when conventional treatment has failed. [48] [49] It is less effective than conventional treatment overall. [48]
Eyewash is a fluid, commonly saline, used to physically wash the eyes in the case that they may be contaminated by foreign materials or substances. Eyewashes may be beneficial to those with sensitive eyes and can provide relief to the painful side effects of sensitivity.
The solution, while unstable, remains effective for at least a week, if made to the correct pH. [17] Other formulations have been developed over time. In 1916, Marcel Daufresne substituted sodium bicarbonate for Dakin's boric acid as buffering agent. [7] [17] This formulation is the basis of current commercial products. [18]
The simplest way to prepare a BBS solution is to use BBS tablets. They are formulated to give a ready to use borate buffered saline solution upon dissolution in 500 ml of deionized water. Concentration of borate and NaCl as well as the pH can vary, and the resulting solution would still be referred to as "borate buffered saline".
Fluoroboric acid is corrosive and attacks the skin. It is available commercially as a solution in water and other solvents such as diethyl ether. It is a strong acid with a weakly coordinating, non-oxidizing conjugate base. [2] It is structurally similar to perchloric acid, but lacks the hazards associated with oxidants.
Polymeric boron oxoanions are formed in aqueous solution of boric acid at pH 7–10 if the boron concentration is higher than about 0.025 mol/L. The best known of these is the tetraborate ion [B 4 O 7 ] 2− , found in the mineral borax:
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