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Neramexane is a drug related to memantine, [1] which acts as an NMDA antagonist [2] and has neuroprotective effects. [3] It is being developed for various possible applications, including treatment of tinnitus, [4] [5] Alzheimer's disease, [6] drug addiction [7] and as an analgesic. [8]
In 2020, information about clinical trials indicated that bimodal neuromodulation may reduce the symptoms of tinnitus. It is a noninvasive technique that involves applying an electrical stimulus to the tongue while also administering sounds. [129] Equipment associated with the treatments is available through physicians.
Tinnitus activities treatment (TAT) is a clinical adaptation of TRT that focuses on four areas: thoughts and emotions, hearing and communication, sleep, and concentration. [13] Progressive tinnitus management (PTM) is a five-step structured clinical protocol for management of tinnitus that may include tinnitus retraining therapy. The five steps ...
Tinnitracks is based on the "Tailor-Made Notched Music Training" ("TMNMT") system. [7] [8] This approach uses filtered music to reduce the tinnitus volume.As emphasised by the name, TMNMT ("Tailor-Made"), the importance of individualisation in calibrating the initial set-up is crucial, and refers both to the patient's individual tinnitus frequency profile and the use of the patient's favourite ...
Since 1980, the organization has granted around $6 million in seed funding for tinnitus research. [7] Many of the researchers have utilized their ATA-funded research data to apply for and receive larger, federally-funded grants from the Department of Defense, National Science Foundation, and the National Institute on Deafness and Other Communications Disorders (NIDCD), part of the NIH.
The DRKS is an open access, free of charge online register for clinical trials and is available both in English and German. DRKS is part of the WHO's ICTRP. The DRKS works with two partner registries in Germany, DeReG (German Registry for Somatic Gene-Transfer Trials) and Clinical Trial Registry of the University Medical Center Freiburg. [4]
The United States Food and Drug Administration's Investigational New Drug (IND) program is the means by which a pharmaceutical company obtains permission to start human clinical trials and to ship an experimental drug across state lines (usually to clinical investigators) before a marketing application for the drug has been approved.
The location of clinical trial sites being used for a study; and A point of contact for patients interested in enrolling in the trial. The National Library of Medicine in the National Institutes of Health made ClinicalTrials.gov available to the public via the internet on February 29, 2000. [ 6 ]