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Ocrelizumab, sold under the brand name Ocrevus, is a medication used for the treatment of multiple sclerosis. It is a humanized anti- CD20 monoclonal antibody . [ 8 ] It targets CD20 marker on B lymphocytes and is an immunosuppressive drug . [ 10 ]
Clinical trial number NCT05232825 for "A Phase III, Non-Inferiority, Randomized, Open-Label, Parallel Group, Multicenter Study To Investigate The Pharmacokinetics, Pharmacodynamics, Safety And Radiological And Clinical Effects Of Subcutaneous Ocrelizumab Versus Intravenous Ocrelizumab In Patients With Multiple Sclerosis (Ocarina II)" at ClinicalTrials.gov
SPS/STD - 'Standard Pressure Setting' or just 'Standard' refers to the altimeter being set to the standard pressure of 1013.25 hPa. It is the setting that causes an altimeter to read the aircraft's flight level (FL). Flight levels are given in hundreds of feet (for example: FL100 = 10 000 ft). Atmospheric pressure changes over time and position.
The altimeter setting used is the ISA sea level pressure of 1013 hPa or 29.92 inHg. The actual surface pressure will vary from this at different locations and times. Therefore, by using a standard pressure setting, every aircraft has the same altimeter setting, and vertical clearance can be maintained during cruise flight. [1]
The cockpit of a Slingsby T-67 Firefly two-seat light airplane.The flight instruments are visible on the left of the instrument panel. Flight instruments are the instruments in the cockpit of an aircraft that provide the pilot with data about the flight situation of that aircraft, such as altitude, airspeed, vertical speed, heading and much more other crucial information in flight.
Altimeter reading when subscale set 1013.25 hPa (atmospheric pressure at sea level in the International Standard Atmosphere) [2] QNH The pressure set on the subscale of the altimeter so that the instrument indicates its height above sea level (the altimeter will read runway elevation when the aircraft is on the runway).
Indicated altitude is the reading on the altimeter when it is set to the local barometric pressure at mean sea level. In UK aviation radiotelephony usage, the vertical distance of a level, a point or an object considered as a point, measured from mean sea level; this is referred to over the radio as altitude.(see QNH) [2]
The altimeter, which is usually a barometer calibrated in units of distance instead of atmospheric pressure, can therefore be set in such a way as to indicate the height of the aircraft above ground. This is done by communicating with the control tower of the airport (to get the current surface pressure) and setting the altimeter so as to read ...