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  2. Endochondral ossification - Wikipedia

    en.wikipedia.org/wiki/Endochondral_ossification

    On the other hand, endochondral ossification starts with mesenchymal tissue turning into an intermediate cartilage stage, which is eventually substituted by bone. [3] Endochondral ossification is responsible for development of most bones including long and short bones, [4] the bones of the axial (ribs and vertebrae) and the appendicular ...

  3. Ossification center - Wikipedia

    en.wikipedia.org/wiki/Ossification_center

    A primary ossification center is the first area of a bone to start ossifying. It usually appears during prenatal development in the central part of each developing bone. In long bones the primary centers occur in the diaphysis/shaft and in irregular bones the primary centers occur usually in the body of the bone. Most bones have only one ...

  4. Ossification - Wikipedia

    en.wikipedia.org/wiki/Ossification

    Diagram showing stages of endochondral ossification. Endochondral ossification is the formation of long bones and other bones. This requires a hyaline cartilage precursor. There are two centers of ossification for endochondral ossification. The primary center. In long bones, bone tissue first appears in the diaphysis (middle of shaft).

  5. Development of joints - Wikipedia

    en.wikipedia.org/wiki/Development_of_joints

    The process of endochondral ossification, which converts the cartilage models into bone, begins by the twelfth week of embryonic development. At birth, ossification of much of the bone has occurred, but the hyaline cartilage of the epiphyseal plate will remain throughout childhood and adolescence to allow for bone lengthening.

  6. Bone healing - Wikipedia

    en.wikipedia.org/wiki/Bone_healing

    The replacement process is known as endochondral ossification with respect to the hyaline cartilage and bony substitution with respect to the woven bone. Substitution of woven bone happens before substitution of hyaline cartilage. The lamellar bone begins forming soon after the collagen matrix of either tissue becomes mineralized.

  7. Osteon - Wikipedia

    en.wikipedia.org/wiki/Osteon

    The Haversian system forms during the process of endochondral ossification, which starts with a cartilage template that is gradually replaced by bone tissue. Osteoblasts , the bone-forming cells, secrete the organic components of bone matrix [osteoid] and then initiates its mineralization.

  8. Bone - Wikipedia

    en.wikipedia.org/wiki/Bone

    Endochondral ossification occurs in long bones and most other bones in the body; it involves the development of bone from cartilage. This process includes the development of a cartilage model, its growth and development, development of the primary and secondary ossification centers, and the formation of articular cartilage and the epiphyseal ...

  9. Chondrocyte - Wikipedia

    en.wikipedia.org/wiki/Chondrocyte

    Endochondral ossification is the process by which most vertebrate axial skeletons form into hardened bones from cartilage. This process begins with a cartilage anlage where chondrocyte cells will congregate and start their maturation process.