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Despite most dissociatives' main mechanism of action being tied to NMDA receptor antagonism, some of these substances, which are nonselective in action and affect the dopamine [2] and/or opioid [3] systems, may be capable of inducing more direct and repeatable euphoria or symptoms which are more akin to the effects of typical "hard drugs" or ...
Dizocilpine (MK-801): an experimental drug used in scientific research. [41] Ethanol: also known as alcohol, a widely used intoxicant. Eticyclidine: a slightly more potent dissociative anesthetic than phencyclidine but with greater nausea/unpleasant taste, that was discontinued early in its development due to these digestive complaints.
Drug 1 Drug 2 Drug 3 Drug 4 Polysubstance slang, [2] [3] [4] or brand name Intoxication name Comment Any dissociative: Any dissociative: Void flip Void flipping Any dissociative: DMT: Dime bar, angel flip Dimension flipping, angel flipping Any depressant: Any stimulant: Speedball, powerball, over and under Powerballing, speedballing [5] Any ...
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This is an accepted version of this page This is the latest accepted revision, reviewed on 6 January 2025. The following is a list of mental disorders as defined at any point by the Diagnostic and Statistical Manual of Mental Disorders (DSM) or the International Classification of Diseases (ICD). A mental disorder, also known as a mental illness, mental health condition, or psychiatric disorder ...
As examples, BTCP is a selective ... 3° alcohol is then reacted with NaN 3; ... a comprehensive review of the non-medical use of dissociative drugs".
Designer drugs are structural or functional analogues of controlled substances that are designed to mimic the pharmacological effects of the parent drug while avoiding detection or classification as illegal.
The central nervous system actions of deliriants are complex, and other muscarinic acetylcholine receptors, including the M 3, M 4, and M 5 receptors, may also be involved in the effects of the drugs. [9] As an example, the M 1, M 2, M 4 and M 5 receptors have all been implicated in regulating dopamine release, with the M 1, M 2, and M 4 ...