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The prostate is a exocrine gland of the male reproductive system. In adults, it is about the size of a walnut, [2] and has an average weight of about 11 grams (0.39 oz), usually ranging between 7 and 16 grams (0.25–0.56 oz). [3] The prostate is located in the pelvis. It sits below the urinary bladder and surrounds the urethra.
Benign prostatic hyperplasia (BPH), also called prostate enlargement, is a noncancerous increase in size of the prostate gland. [1] Symptoms may include frequent urination , trouble starting to urinate, weak stream, inability to urinate , or loss of bladder control . [ 1 ]
Gleason 3 is a clearly infiltrative neoplasm, with extension into adjacent healthy prostate tissue. The glands alternate in size and shape, and are often long/angular. They are usually small/micro-glandular in comparison to Gleason 1 or 2 grades. However, some may be medium to large in size.
The International Prostate Symptom Score (IPSS) is an eight-question written screening tool used to screen for, rapidly diagnose, track the symptoms of, and suggest management of the lower urinary tract symptoms of benign prostatic hyperplasia (BPH).
In a 2015 articles in the Journal of Urology, Thompson reported multi-parametric MRI detection of significant prostate cancer had sensitivity of 96%, specificity of 36%, negative predictive value and positive predictive values of 92% and 52%; when PI-RADS was incorporated into a multivariate analysis (PSA, digital rectal exam, prostate volume ...
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Digital rectal examination (DRE), also known as a prostate exam (Latin: palpatio per anum (PPA), lit. 'palpation through the anus'), is an internal examination of the rectum performed by a healthcare provider .
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