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  2. Tacrolimus - Wikipedia

    en.wikipedia.org/wiki/Tacrolimus

    The most common adverse events associated with the use of topical tacrolimus ointments, especially if used over a wide area, include a burning or itching sensation on the initial applications, with increased sensitivity to sunlight and heat on the affected areas. [citation needed] Less common are flu-like symptoms, headache, cough, and burning ...

  3. mTOR inhibitors - Wikipedia

    en.wikipedia.org/wiki/MTOR_inhibitors

    mTOR inhibitors are a class of drugs used to treat several human diseases, including cancer, autoimmune diseases, and neurodegeneration. They function by inhibiting the mammalian target of rapamycin (mTOR) (also known as the mechanistic target of rapamycin), which is a serine/threonine-specific protein kinase that belongs to the family of phosphatidylinositol-3 kinase (PI3K) related kinases ...

  4. Immunosuppressive drug - Wikipedia

    en.wikipedia.org/wiki/Immunosuppressive_drug

    Tacrolimus (trade names Prograf, Astagraf XL, Envarsus XR) is a product of the bacterium Streptomyces tsukubensis. It is a macrolide lactone and acts by inhibiting calcineurin . The drug is used primarily in liver and kidney transplantations, although in some clinics it is used in heart, lung, and heart/lung transplantations.

  5. List of psychiatric medications by condition treated - Wikipedia

    en.wikipedia.org/wiki/List_of_psychiatric...

    This is a list of psychiatric medications used by psychiatrists and other physicians to treat mental illness or distress. The list is ordered alphabetically according to the condition or conditions, then by the generic name of each medication. The list is not exhaustive and not all drugs are used regularly in all countries.

  6. BK virus - Wikipedia

    en.wikipedia.org/wiki/BK_virus

    In some renal transplant patients, the necessary use of immunosuppressive drugs has the side-effect of allowing the virus to replicate within the graft, a disease called BK nephropathy. [7] From 1–10% of renal transplant patients progress to BK virus associated nephropathy (BKVAN) and up to 80% of these patients lose their grafts.

  7. WHO Model List of Essential Medicines for Children - Wikipedia

    en.wikipedia.org/wiki/WHO_Model_List_of...

    The selection and use of essential medicines: report of the WHO Expert Committee, 2017 (including the 20th WHO Model List of Essential Medicines and the 6th Model List of Essential Medicines for Children). Geneva: World Health Organization. hdl: 10665/259481. ISBN 978-92-4-121015-7. ISSN 0512-3054. WHO technical report series; no. 1006.

  8. Ascomycin - Wikipedia

    en.wikipedia.org/wiki/Ascomycin

    Ascomycin, also called Immunomycin, FR-900520, FK520, is an ethyl analog of tacrolimus (FK506) with strong immunosuppressant properties. It has been researched for the treatment of autoimmune diseases and skin diseases, and to prevent rejection after an organ transplant.

  9. Pimecrolimus - Wikipedia

    en.wikipedia.org/wiki/Pimecrolimus

    Pimecrolimus has a similar mode of action to that of tacrolimus but is more selective, with no effect on dendritic (Langerhans) cells. [19] It has lower permeation through the skin than topical steroids or topical tacrolimus [20] although they have not been compared with each other for their permeation ability through mucosa. In addition, in ...

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