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Cordycepin, or 3'-deoxyadenosine, is a derivative of the nucleoside adenosine, differing from the latter by the replacement of the hydroxy group in the 3' position with a hydrogen. It was initially extracted from the fungus Cordyceps militaris , [ 1 ] but can now be produced synthetically. [ 2 ]
[7] [8] These make it potentially valuable as an additive into health foods, particularly selenium containing ones, and potentially as a cancer treatment. [9] C. gunnii mycelia has also been found to contain cordycepin, cordycepic acid, polysaccharides and anti-ultraviolet radiation constituents. [10]
Like other members of the Cordyceps genus, C. militaris produces the pharmacologically active compound cordycepin. Cordycepin is a nucleoside analogue of adenosine-differing by only a single hydroxyl group. It has been shown to induce apoptosis, reduce inflammation, and inhibit RNA transcription in cell cultures.
Cordyceps / ˈ k ɔːr d ɪ s ɛ p s / is a genus of ascomycete fungi (sac fungi) that includes over 260 species worldwide, many of which are parasitic. Diverse variants of cordyceps have had more than 1,500 years of use in Chinese medicine. [1]
For example, such enzyme is overexpressed in patients who suffer from cancer; that's why it can be used as a prognostic factor for early appearance in breast cancer patients. Moreover, PAP activity is used to measure the effect of anticancer drugs as etoposide and cordycepin in two carcinoma cell lines: HeLa , which is the human epithelioid ...
Cordycepin, a compound isolated from the "caterpillar fungus". In traditional Chinese medicine, it is regarded as having an excellent balance of yin and yang as it is considered to be composed of both an animal and a vegetable. [29] They are now cultivated on an industrial scale for their use in traditional Chinese medicine.
There can be many years between promising laboratory work and the availability of an effective anti-cancer drug: Monroe Eliot Wall discovered anti-cancer properties in Camptotheca in 1958, but it was not until 1996 – after further research and rounds of clinical trials – that topotecan, a synthetic derivative of a chemical in the plant, was ...
C cell – c-erbB-2 – c-kit – CA 19-9 assay – CA-125 – CA-125 test – cachexia – calcitonin – calcitriol – CAM – Campath-1H – camptothecin – camptothecin analog – cancer – cancer induction – Cancer Information Service – cancer of unknown primary origin – cancer stem cell – cancer vaccine – Cancer.gov – Candidiasis – Candidosis – CAP-1 – capecitabine ...