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Liver toxicity, allergic reaction, anaphylaxis [3] Kava: awa, kava-kava [4] Piper methysticum: Potentiates CNS sedatives, [3] chronic use might cause a reversible dry skin condition. [18] Khat: qat Catha edulis: Chronic liver dysfunction [3] [19] Kratom: Mitragyna speciosa: Hepatotoxicity [20] [19] Liquorice root Glycyrrhiza glabra
Kava is not a psychedelic like magic mushrooms or LSD or a dissociative like ketamine and it should not be used for psychedelic or dissociative purposes. This use is highly dangerous and can result in liver damage or other serious side effects.
Data from the Drug Induced Liver Injury Network show that rates of liver injury from botanical products jumped from seven percent in 2004-2005 to 20 percent in 2013-2014.
Data from Drug Induced Liver Injury Network reported the rates of liver injury due to botanical products has been on the rise from 7% in 2004-2005 to 20% in 2013-2014.
Methysticin is one of the six major kavalactones found in the kava plant. [1] Research suggests that methysticin and the related compound dihydromethysticin have CYP1A1 inducing effects which may be responsible for their toxicity. [2]
Supplements That Damage the Liver The supplements the study mentioned include: Ashwagandha , used to support the nervous and endocrine systems; improve sleep; and boost mood, energy and immune levels
New research has found that six herbal supplements that are popular on TikTok may cause liver damage. Researchers at the University of Michigan concluded that supplements, including Ashwagandha ...
Kavalactones are a class of lactone compounds found in kava roots and Alpinia zerumbet (shell ginger). [1] and in several Gymnopilus, Phellinus and Inonotus fungi. [2] Some kavalactones are bioactive. They are responsible for the psychoactive, analgesic, euphoric and sedative effects of kava. [3] [4]