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Dermatophagoides pteronyssinus Dust mite faecal pellets that can be small as 10 μm, [1] but can be contained by anti-mite fabrics of a denser pore size. [2]House dust mites (HDM, or simply dust mites) are various species of acariform mites belonging to the family Pyroglyphidae that are found in association with dust in dwellings. [3]
2,4-Dichlorophenoxyacetic acid (2,4-D) is a common herbicide for controlling weeds, and it has been reported to be a mutagen. [30] A study has shown that A. penicillioides can remove 2,4-D from synthetic liquid media. [30] There was a lag period of 1 day, followed by 52% removal of 2,4-D from culture media by A. penicillioides. [30]
The first allergen to be purified and characterized was Der p 1, in a 1980 study by Martin D. Chapman and Thomas Platts-Mills. [10] [11] By the end of the decade, it was suspected that Der p 1 was a cysteine protease when its structure showed similarities to that of actinidin and papain. [12]
From this perspective, D-values can be understood as roughly analogous to half lives of radioactive substances, however a half life involves a reduction of 50% rather than 90%. The half life is actually roughly 30% (log 10 2 ≈ 30.103%) of the D-value, so if D = 10 minutes, the number of living microorganisms will be halved in about 3 minutes.
In technical terms, an allergen is an antigen that is capable of stimulating a type-I hypersensitivity reaction in atopic individuals through immunoglobulin E (IgE) responses. [1] Most humans mount significant Immunoglobulin E responses only as a defense against parasitic infections. However, some individuals may respond to many common ...
The IgG, IgE and IgA antibody isotypes are generated following class-switching during germinal centre reaction and provide different effector functions in response to specific antigens. IgG is the most abundant antibody class in the serum and it is divided into 4 subclasses based on differences in the structure of the constant region genes and ...
The idea of a link between parasite infection and immune disorders was first suggested in 1968 [13] before the advent of large scale DNA sequencing techniques.The original formulation of the hygiene hypothesis dates from 1989, when David Strachan proposed that lower incidence of infection in early childhood could be an explanation for the rise in allergic diseases such as asthma and hay fever ...
The RAST is a radioimmunoassay test to detect specific IgE antibodies to suspected or known allergens for the purpose of guiding a diagnosis about allergy. [10] [11] IgE is the antibody associated with Type I allergic response: for example, if a person exhibits a high level of IgE directed against pollen, the test may indicate the person is allergic to pollen (or pollen-like) proteins.