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Dextromethorphan, sold under the brand name Robitussin among others, is a cough suppressant used in many cough and cold medicines. [6] In 2022, the US Food and Drug Administration (FDA) approved the combination dextromethorphan/bupropion to serve as a rapid-acting antidepressant in people with major depressive disorder.
This mechanism is most likely responsible for the mucolytic effects of the drug, but may also explain the reported activity in Gaucher and Parkinson's disease. Both ambroxol and its parent drug bromhexine have been shown to induce autophagy in several cell types, and ambroxol was shown to potentiate rifampicin therapy in a model of tuberculosis ...
Methylephedrine, sold under the brand name Metheph among others, is a sympathomimetic medication described as an antiasthmatic agent and used to treat coughing and nasal congestion. [ 3 ] [ 4 ] [ 1 ] It is reported to be used in various over-the-counter cough and cold preparations throughout the world, including Japan .
A dry cough, on the other hand, is commonly associated with irritated or inflamed upper airways, says Glen B. Chun, M.D., an assistant professor of medicine and clinical director of Mount Sinai's ...
Diabetic nephropathy, also known as diabetic kidney disease, [5] is the chronic loss of kidney function occurring in those with diabetes mellitus. Diabetic nephropathy is the leading causes of chronic kidney disease (CKD) and end-stage renal disease (ESRD) globally. The triad of protein leaking into the urine (proteinuria or albuminuria ...
Clofedanol or chlophedianol , sold under the brand name Ninjacof among others, is a centrally acting cough suppressant used in the treatment of dry cough. Clofedanol has local anesthetic , antispasmodic , and antihistamine properties, [ 1 ] and may have anticholinergic effects at high doses.
The trial called FLOW started in 2019 and involved roughly 3,500 patients with type 2 diabetes and moderate to severe chronic kidney disease, who were given 1 milligram (mg) of once-weekly ...
Choline theophyllinate , also known as oxtriphylline, is a cough medicine derived from xanthine that acts as a bronchodilator to open up airways in the lung. Chemically, it is a salt of choline and theophylline. It classifies as an expectorant.
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