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4654 17927 Ensembl ENSG00000129152 ENSMUSG00000009471 UniProt P15172 P10085 RefSeq (mRNA) NM_002478 NM_010866 RefSeq (protein) NP_002469 NP_034996 Location (UCSC) Chr 11: 17.72 – 17.72 Mb Chr 7: 46.03 – 46.03 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse MyoD, also known as myoblast determination protein 1, is a protein in animals that plays a major role in regulating muscle ...
Myogenic regulatory factors (MRF) are basic helix-loop-helix (bHLH) transcription factors that regulate myogenesis: MyoD, Myf5, myogenin, and MRF4. [1]These proteins contain a conserved basic DNA binding domain that binds the E box DNA motif. [2]
(G71.0) Dystrophies (or muscular dystrophies) are a subgroup of myopathies characterized by muscle degeneration and regeneration. Clinically, muscular dystrophies are typically progressive, because the muscles' ability to regenerate is eventually lost, leading to progressive weakness, often leading to use of a wheelchair, and eventually death, usually related to respiratory weakness.
Myotonic dystrophy (DM) is a type of muscular dystrophy, a group of genetic disorders that cause progressive muscle loss and weakness. [1] In DM, muscles are often unable to relax after contraction. [1]
Myocardial infarction; Other names: Acute myocardial infarction (AMI), heart attack: A myocardial infarction occurs when an atherosclerotic plaque slowly builds up in the inner lining of a coronary artery and then suddenly ruptures, causing catastrophic thrombus formation, totally occluding the artery and preventing blood flow downstream to the heart muscle.
Myocarditis is defined as inflammation of the myocardium.Myocarditis can progress to inflammatory cardiomyopathy when there are associated ventricular remodeling and cardiac dysfunction due to chronic inflammation.
Most myosin molecules are composed of a head, neck, and tail domain.. The head domain binds the filamentous actin, and uses ATP hydrolysis to generate force and to "walk" along the filament towards the barbed (+) end (with the exception of myosin VI, which moves towards the pointed (-) end).
Electromyography (EMG) is a technique for evaluating and recording the electrical activity produced by skeletal muscles. [1] [2] EMG is performed using an instrument called an electromyograph to produce a record called an electromyogram.