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Tryptophan. Soluble in hot alcohol, alkali hydroxides; insoluble in chloroform. Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Tryptophan (symbol Trp or W) [3] is an α- amino acid that is used in the biosynthesis of proteins.
Rheumatology. Eosinophilia–myalgia syndrome is a rare, sometimes fatal neurological condition linked to the ingestion of the dietary supplement L-tryptophan. [1][2] The risk of developing EMS increases with larger doses of tryptophan and increasing age. [3] Some research suggests that certain genetic polymorphisms may be related to the ...
5-Hydroxytryptophan (5-HTP), used medically as oxitriptan, is a naturally occurring amino acid and chemical precursor as well as a metabolic intermediate in the biosynthesis of the neurotransmitter serotonin. 5-HTP can be manufactured and used as a drug and supplement with the INN oxitriptan. Brand names include Cincofarm, Levothym, Levotonine ...
Essential amino acid. An essential amino acid, or indispensable amino acid, is an amino acid that cannot be synthesized from scratch by the organism fast enough to supply its demand, and must therefore come from the diet. Of the 21 amino acids common to all life forms, the nine amino acids humans cannot synthesize are valine, isoleucine ...
Infobox references. l-Kynurenine is a metabolite of the amino acid l - tryptophan used in the production of niacin. Kynurenine is synthesized by the enzyme tryptophan dioxygenase, which is made primarily but not exclusively in the liver, and indoleamine 2,3-dioxygenase, which is made in many tissues in response to immune activation. [1]
Tryptophan 2,3-dioxygenase. In enzymology, tryptophan 2,3-dioxygenase (EC 1.13.11.11) is a heme enzyme that catalyzes the oxidation of L - tryptophan (L -Trp) to N -formyl- L -kynurenine, as the first and rate-limiting step of the kynurenine pathway. Tryptophan 2,3-dioxygenase plays a central role in the physiological regulation of tryptophan ...
α-Methyltryptophan (αMTP or α-MTP) is a synthetic tryptamine derivative, an artificial amino acid, and a prodrug of α-methylserotonin (αMS). [1] [2] [3] It is the α-methylated derivative of tryptophan, while αMS is the α-methylated analogue of serotonin.
Monoamine precursor. L -Tryptophan, a precursor of serotonin and melatonin and an example of a monoamine precursor. Monoamine precursors are precursors of monoamines and monoamine neurotransmitters in the body. [1][2] The amino acids L -tryptophan and L -5-hydroxytryptophan (5-HTP; oxitriptan) are precursors of serotonin and melatonin, while ...
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