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Treatment using these targets can supplement or replace some of the intensive chemotherapy that is used for neuroblastoma. These molecular targets of this disease include GD2 , ALK , and CD133 . GD2 is a target of immunotherapy , and is the most fully developed of these treatment methods, but is also associated with toxicities. [ 1 ]
Neuroblastoma (NB) is a type of cancer that forms in certain types of nerve tissue. [1] It most frequently starts from one of the adrenal glands but can also develop in the head, neck, chest, abdomen, or spine. [1]
The Neuroblastoma Alliance UK helps families access and fundraise for their child's treatment abroad. Various new treatments for neuroblastoma are being trialled in the UK, but if children do not meet the criteria for a trial, or need treatment that is only available abroad, families have to pay for their child's treatment abroad.
This is an accepted version of this page This is the latest accepted revision, reviewed on 18 January 2025. There is 1 pending revision awaiting review. Neoplasm in the brain Medical condition Brain tumor Other names Intracranial neoplasm, brain tumour, brain cancer Brain metastasis in the right cerebral hemisphere from lung cancer, shown on magnetic resonance imaging Specialty Neurosurgery ...
Chemotherapy is used in a multimodality treatment plan generally for more advanced, unresectable or reoccurring tumors. [4] Cyclophosphamide, vincristine and doxorubicin have been used as neoadjuvant chemotherapy drugs for grade C esthesioneuroblastoma before surgical resection, producing fair outcomes.
Neuroblastoma is a cancer more frequently affecting children, and despite the relatively low rates of anti-Hu among children with neuroblastoma, these are the most likely children to have anti-Hu associated encephalitis. [8] [9]
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Since neurologic and developmental difficulties have not been reported as a consequence of neuroblastoma or its treatment, it is thought that these are exclusively due to the immune mechanism underlying OMS. [24] One study concludes that: "Patients with OMA and neuroblastoma have excellent survival but a high risk of neurologic sequelae ...