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Nikolsky's sign is a clinical dermatological sign, named after Pyotr Nikolsky (1858–1940), a Russian physician who trained and worked in the Russian Empire. The sign is present when slight rubbing of the skin results in exfoliation of the outermost layer.
The disease presents with the widespread formation of fluid-filled blisters that are thin walled and easily ruptured, and the patient can be positive for Nikolsky's sign. SSSS bears a resemblance to thermal burns or scalding , hence the condition's name.
The Asboe-Hansen sign (also known as "indirect Nikolsky sign'" [1] or "Nikolsky II sign" [1]) refers to the extension of a large blister to adjacent unblistered skin when pressure is put on the top of it.
Pages in category "Dermatologic signs" The following 20 pages are in this category, out of 20 total. ... Nikolsky's sign; Nodule (medicine) R. Renbök phenomenon;
Nikolsky's sign (gentle lateral pressure) on unaffected mucosa or skin raises a bulla. If no lesions are present on examination it may be useful way of demonstrating reduced epithelial adhesion. If no lesions are present on examination it may be useful way of demonstrating reduced epithelial adhesion.
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The Nikolsky sign (a separation of the papillary dermis from the basal layer upon gentle lateral pressure) and the Asboe-Hansen sign (a lateral extension of bullae with pressure) are also helpful diagnostic signs found in patients with TEN. [7]