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It is similar to friability testing, [1] but they are not the same thing. Tablet hardness testers first appeared in the 1930s. [3] In the 1950s, the Strong-Cobb tester was introduced. It was patented by Robert Albrecht on July 21, 1953. [4] and used an air pump. The tablet breaking force was based on arbitrary units referred to as Strong-Cobbs. [3]
Schleuniger already held a minority interest in DiIT AG, a producer of software for wire processing and wiring harness production, prior to taking full ownership. As of January 1, 2017 the previous majority stakeholder and company founder, Dr. Gerhard Schaub, sold all of his shares to Schleuniger and left the company at his own request.
Models of testers include the Monsanto (or Stokes) Hardness Tester from 1930, the Pfizer Hardness Tester from 1950, the Strong Cob Hardness Tester and the Heberlain (or Schleeniger) Hardness Tester. Lubricants prevent ingredients from clumping together and from sticking to the tablet punches or capsule filling machine.
In the pharmaceutical industry, drug dissolution testing is routinely used to provide critical in vitro drug release information for both quality control purposes, i.e., to assess batch-to-batch consistency of solid oral dosage forms such as tablets, and drug development, i.e., to predict in vivo drug release profiles. [1]
User guides have been found with ancient devices. One example is the Antikythera Mechanism, [1] a 2,000 year old Greek analogue computer that was found off the coast of the Greek island Antikythera in the year 1900. On the cover of this device are passages of text which describe the features and operation of the mechanism.
A tablet press in operation An old rotary tablet press. A tablet press is a mechanical device that compresses powder into tablets of uniform size and weight. A tablet press can be used to manufacture tablets of a wide variety of materials, including pharmaceuticals, nutraceuticals, cleaning products, industrial pellets and cosmetics.
Typical lectromechanical Universal Testing Machine Test fixture for three point flex test. A universal testing machine (UTM), also known as a universal tester, [1] universal tensile machine, materials testing machine, materials test frame, is used to test the tensile strength (pulling) and compressive strength (pushing), flexural strength, bending, shear, hardness, and torsion testing ...
The 24th Century Technical Manual Special Edition 1989, 1. No publisher listed. 1989. Christopher Simmons. The 24th Century Technical Manual Special Edition 1989, 2.